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匹伐他汀乙酯

匹伐他汀乙酯

CAS号：167073-19-0

英文名：Pitavastatin ethyl ester

分子式

C27H28FNO4

熔点

密度

1.27g/cm3

分子量

449.514

沸点

428.7ºC at 760 mmHg

溶解度

信号词

危险品标志

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基本信息

中文名称

匹伐他汀乙酯

英文名称

Pitavastatin ethyl ester

中文别名

英文别名

5-dihydroxy-6-heptenoic acid ethyl ester

CAS号

167073-19-0

分子式

C27H28FNO4

分子量

449.514

精确质量

449.2

PSA

79.65

LOGP

4.9966

编号系统

MDL号

MFCD09751109

物化性质

密度

1.27g/cm3

沸点

428.7ºC at 760 mmHg

闪点

213.1ºC

折射率

1.53

蒸汽压

1.49E-07mmHg at 25°C

合成路线

ethyl 5(S)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate

ethyl 5(S)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate

匹伐他汀乙酯

匹伐他汀乙酯

上游原料

共找到12个上游原料 >

(S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-1-(1H-imidazol-1-yl)pent-4-en-1-one

(S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-1-(1H-imidazol-1-yl)pent-4-en-1-one

methyl (2E)-3-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]acrylate

methyl (2E)-3-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]acrylate

(S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)pent-4-enoic acid

(S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)pent-4-enoic acid

ethyl 5(R)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate

ethyl 5(R)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate

(E)-3-[2-环丙基-4-(4-氟苯基)-3-喹啉-2-丙烯醛

(E)-3-[2-环丙基-4-(4-氟苯基)-3-喹啉-2-丙烯醛

(3S,4E)-5-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-3-hydroxypentenoic acid

(3S,4E)-5-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-3-hydroxypentenoic acid

上游原料

(S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-1-(1H-imidazol-1-yl)pent-4-en-1-one methyl (2E)-3-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]acrylate (S,E)-3-((tert-butyldimethylsilyl)oxy)-5-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)pent-4-enoic acid ethyl 5(R)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate (E)-3-[2-环丙基-4-(4-氟苯基)-3-喹啉-2-丙烯醛 (3S,4E)-5-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-3-hydroxypentenoic acid 2-环丙基-4-(4-氟苯基)喹啉-3-甲醛 ethyl 5(S)-(E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-5-hydroxy-3-oxo-6-heptenoate ethyl (E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-quinolin-3-yl]-3,5-dihydroxyhept-6-enoate (E)-7-[2-cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dioxo-hept-6-enoic acid ethyl ester ethyl (5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinoline-3-yl]-5-(tert-butyldimethylsilyloxy)-3-oxo-6-heptenoate