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丁胺苯丙酮

丁胺苯丙酮

CAS号：170364-57-5

英文名：3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione

分子式

C32H29N5O2

熔点

密度

1.34g/cm3

分子量

515.605

沸点

767.2ºC at 760mmHg

溶解度

信号词

Warning

危险品标志

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化合物简介

Enzastaurin is a synthetic bisindolylmaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply, preventing growth.

基本信息

中文名称

丁胺苯丙酮

英文名称

3-(1-Methyl-1H-indol-3-yl)-4-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)-1H-pyrrole-2,5-dione

中文别名

恩扎妥林、2-氧杂-6-氮杂螺[3,3]庚烷草酸盐、3-(1-甲基-1H-吲哚-3-基)-4-(1-(1-(2-吡啶甲基)-4-哌啶基)-1H-吲哚-3-基)-1H-吡咯-2,5-二酮

英文别名

3-(1-methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione、Enzastaurin

CAS号

170364-57-5

分子式

C32H29N5O2

分子量

515.605

精确质量

515.232

PSA

72.16

LOGP

5.199

编号系统

MDL号

MFCD11040980

物化性质

密度

1.34g/cm3

沸点

767.2ºC at 760mmHg

闪点

417.8ºC

折射率

1.722

蒸汽压

1.87E-23mmHg at 25°C

安全信息

海关编码

2933990090

信号词

Warning

危险性描述

H302; H413

危险标志

GHS07

生产方法及用途

用途

丝氨酸/羟丁氨酸激酋每抑制剂

合成路线

共找到1条合成路线 >

甲基(1-甲基吲哚基)-3-乙醛酸酯

甲基(1-甲基吲哚基)-3-乙醛酸酯

2-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)acetamide

2-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)acetamide

丁胺苯丙酮

丁胺苯丙酮

上游原料

共找到28个上游原料 >

1-甲基吲哚-3-乙酰胺

1-甲基吲哚-3-乙酰胺

1-哌啶-4-基-1H-吲哚

1-哌啶-4-基-1H-吲哚

N,N-bis(2-ethoxycarbonylethyl)-N-(2-pyridilmethyl)amine

N,N-bis(2-ethoxycarbonylethyl)-N-(2-pyridilmethyl)amine

4-吲哚啉-1-哌啶-1-羧酸叔丁酯

4-吲哚啉-1-哌啶-1-羧酸叔丁酯

1-(2,2-Dimethoxyethyl)-2-nitrobenzene

1-(2,2-Dimethoxyethyl)-2-nitrobenzene

4-(吲哚-1-基)哌啶甲酸叔丁酯

4-(吲哚-1-基)哌啶甲酸叔丁酯

下游产品

共找到1个下游商品 >

3-(1-methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione,hydrochloride

3-(1-methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione,hydrochloride

上游原料

1-甲基吲哚-3-乙酰胺 1-哌啶-4-基-1H-吲哚 N,N-bis(2-ethoxycarbonylethyl)-N-(2-pyridilmethyl)amine 4-吲哚啉-1-哌啶-1-羧酸叔丁酯 1-(2,2-Dimethoxyethyl)-2-nitrobenzene 4-(吲哚-1-基)哌啶甲酸叔丁酯 2-[1-(piperidin-4-yl)-1H-indol-3-yl]-acetamide 1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)indoline 1-[2-(2-nitrophenyl)ethenyl]pyrrolidine (1-methyl-1H-indol-3-yl)-oxo-acetyl chloride oxo-[1-(1-pyridin-2-ylmethyl-piperidin-4-yl)-1H-indol-3-yl]-oxo-acetic acid methyl ester N-甲基吲哚 1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indole 1-(1-Benzyl-piperidin-4-yl)-1H-indole LY 326020 2-(溴甲基)吡啶氢溴酸盐 1-((吡啶-2-基)甲基)-4-哌啶酮 2-氨甲基吡啶 2-(2,2-二甲氧基乙基)苯甲酰胺 3-吲哚乙酰胺 2-(2,3-dihydro-1H-indol-3-yl)acetamide 2-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)indolin-3-yl)acetamide 吲哚啉 N-叔丁氧羰基-4-哌啶酮 4-(3-carbamoylmethyl-1-indol-1-yl)-piperidine-1-carboxylic acid tert-butyl ester tert-butyl 4-(3-(2-amino-2-oxoethyl)indolin-1-yl)piperidine-1-carboxylate 2-(1-(1-(pyridin-2-ylmethyl)piperidin-4-yl)-1H-indol-3-yl)acetamide 甲基(1-甲基吲哚基)-3-乙醛酸酯

下游产品

3-(1-methylindol-3-yl)-4-[1-[1-(pyridin-2-ylmethyl)piperidin-4-yl]indol-3-yl]pyrrole-2,5-dione,hydrochloride