百科

吉米沙星

CAS号：175463-14-6

英文名：gemifloxacin

分子式

C18H20FN5O4

熔点

密度

1.64g/cm3

分子量

389.381

沸点

638.9ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

Gemifloxacin mesylate (trade name Factive, Oscient Pharmaceuticals) is an oral broad-spectrum quinolone antibacterial agent used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Vansen Pharma Inc. has licensed the active ingredient from LG Life Sciences of Korea.

基本信息

中文名称

吉米沙星

英文名称

gemifloxacin

中文别名

7-[3-(氨甲基)-4-(甲氧亚氨基)吡咯烷-1-基]-1-环丙基-6-氟-4-氧代-1,4-二氢-1,8-二氮杂萘-3-羧酸

英文别名

(R,S)-7-(3-aminomethyl-4-syn-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid、Gemifloxactin、Gemifioxacin、Gemifloxacin Mesilate、7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Mesilate、7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid、Gemifloxacin、7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid、7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphtyridine-3-carboxylic acid、7-[3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid、7-(3-Aminomethyl)-4-methoxyimino-pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1

CAS号

175463-14-6

分子式

C18H20FN5O4

分子量

389.381

精确质量

389.15

PSA

123.04

LOGP

1.7313