化合物简介
Mestilbol (brand name Monomestro or Monomestrol), also known as diethylstilbestrol monomethyl ether, is a synthetic, non-steroidal estrogen of the stilbestrol group related to diethylstilbestrol. It was developed by Wallace & Tiernan Company, patented in 1940, and introduced for medical use in the 1940s, but is now no longer marketed. Mestilbol was available both as oral tablets and in oil for intramuscular injection. The drug is gradually demethylated in the body into diethylstilbestrol and hence is a prodrug of diethylstilbestrol. Mestilbol is a highly active estrogen, although somewhat less so than diethylstilbestrol, but is longer-lasting in comparison.
基本信息
中文名称
(E)-4-(1-乙基-2-(4-甲氧基苯基)-1-丁烯基)苯酚
英文名称
4-[(3E)-4-(4-Methoxyphenyl)-3-hexen-3-yl]phenol
中文别名
英文别名
4-[1-Aethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol、(E)-4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-phenol、Monozol、4-[1-Aethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol、trans-4-(1-Ethyl-2-(4-(phenylmethoxy)phenyl)-1-butenyl)phenol、Pituitrope、Hypantin、Phenol, 4-[1-ethyl-2-(4-methoxyphenyl)-1-butenyl]-, (E)-、4-[1-ethyl-2-(4-methoxy-phenyl)-but-1-en-c-yl]-phenol、4-[1-ethyl-2-(4-benzyloxy-phenyl)-but-1-en-c-yl]-phenol、Stilbestrol monobenzyl ether
CAS号
18839-90-2
分子式
C19H22O2
分子量
282.377
精确质量
282.162
PSA
29.46
LOGP
5.1316
编号系统
UNII
N44U12UW5N
物化性质
密度
1.054g/cm3
沸点
413.1ºC at 760mmHg
闪点
192.2ºC
折射率
1.571
蒸汽压
2.06E-07mmHg at 25°C
安全信息
海关编码
2909500000
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