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(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-三-{[叔-丁基(二甲基)硅烷基]氧基}-1-羟基-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七-12,16-二烯-5-酮
CAS号:193146-53-1
英文名:(3S,7S,8S,12Z,15S,16E)-3,7,15-tris[[tert-butyl(dimethyl)silyl]oxy]-1-hydroxy-4,4,6,8,12,16-hexamethyl-17-(2-methyl-1,3-thiazol-4-yl)heptadeca-12,16-dien-5-one
分子式:C45H87NO5SSi3
分子量:838.497
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上游原料
184246-38-6
(2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde
193146-27-9
(2S,6Z,9S,10E)-9-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienal
121587-29-9
(3S)-3-methyl-1-phenylsulfonylbutan-4-ol
187283-43-8
(5S)-5-hydroxy-4,4-dimethyloct-7en-3-one
193146-29-1
(3S)-3-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethyl-5-oxo-heptanal
106921-60-2
2,2-Dimethyl-3-oxopentanal
193146-44-0
(S,4Z,8E)-7-((tert-butyldimethylsilyl)oxy)-4,8-dimethyl-9-(2-methylthiazol-4-yl)nona-4,8-dien-1-ol
193146-40-6
methyl (S,2E,6E)-2-allyl-5-((tert-butyldimethylsilyl)oxy)-6-methyl-7-(2-methylthiazol-4-yl)hepta-2,6-dienoate
193146-46-2
(6Z,10E)-(2S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-2,6,10-trimethyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dienenitrile
193146-42-8
39238-07-8
4-(氯甲基)-2-甲基-1,3-噻唑
263900-30-7
(-)-(3S)-4-{[tert-butyl(diphenyl)silyl]oxy}-3-methylbutyl phenyl sulfone
218614-13-2
(-)-甲基(3S)-3,5-二-{[叔-丁基二甲基硅烷基)氧基]}-2,2-二甲基戊酸酯
263900-32-9
(+)-甲基(3S)-5-{[叔-丁基二甲基硅烷基)氧基]}-3-羟基-2,2-二甲基戊酸酯
20949-84-2
2-甲基-1,3-噻唑-4-甲醛
250679-53-9
(5S)-5-{[(tert-butyl)dimethylsilyl]oxy}-7-hydroxy-4,4-dimethylheptan-3-one
188730-05-4
(1E)(3S)-3-(tert-butyl-dimethylsilyl)oxy-2-methyl-1-[2-methyl(1,3-thiazol-4-yl)]hexa-1,5-diene
355009-03-9
(S)-phenyl 5-((tert-butyldimethylsilyl)oxy)-3-hydroxy-2,2-dimethylpentanoate
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上游原料
(2E)-2-Methyl-3-(2-methyl-1,3-thiazol-4-yl)acrylaldehyde
(2S,6Z,9S,10E)-9-{[tert-butyl(dimethyl)silyl]oxy}-2,6,10-trimethyl-11-(2-methyl-1,3-thiazol-4-yl)undeca-6,10-dienal
(3S)-3-methyl-1-phenylsulfonylbutan-4-ol
(5S)-5-hydroxy-4,4-dimethyloct-7en-3-one
(3S)-3-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethyl-5-oxo-heptanal
2,2-Dimethyl-3-oxopentanal
(S,4Z,8E)-7-((tert-butyldimethylsilyl)oxy)-4,8-dimethyl-9-(2-methylthiazol-4-yl)nona-4,8-dien-1-ol
methyl (S,2E,6E)-2-allyl-5-((tert-butyldimethylsilyl)oxy)-6-methyl-7-(2-methylthiazol-4-yl)hepta-2,6-dienoate
(6Z,10E)-(2S,9S)-9-(tert-Butyl-dimethyl-silanyloxy)-2,6,10-trimethyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dienenitrile
4-(氯甲基)-2-甲基-1,3-噻唑
(-)-(3S)-4-{[tert-butyl(diphenyl)silyl]oxy}-3-methylbutyl phenyl sulfone
(-)-甲基(3S)-3,5-二-{[叔-丁基二甲基硅烷基)氧基]}-2,2-二甲基戊酸酯
(+)-甲基(3S)-5-{[叔-丁基二甲基硅烷基)氧基]}-3-羟基-2,2-二甲基戊酸酯
2-甲基-1,3-噻唑-4-甲醛
(5S)-5-{[(tert-butyl)dimethylsilyl]oxy}-7-hydroxy-4,4-dimethylheptan-3-one
(1E)(3S)-3-(tert-butyl-dimethylsilyl)oxy-2-methyl-1-[2-methyl(1,3-thiazol-4-yl)]hexa-1,5-diene
(S)-phenyl 5-((tert-butyldimethylsilyl)oxy)-3-hydroxy-2,2-dimethylpentanoate
4-((1E,3S,5Z)-3-{[tert-butyl(dimethyl)silyl]oxy}-7-iodo-2,6-dimethylhepta-1,5-dienyl)-2-methyl-1,3-thiazole
(3S,6R,7S,8S,12Z,15S,16E)-1,3,7,15-四-{[叔-丁基(二甲基)硅烷基]氧基}-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七-12,16-二烯-5-酮
叔丁基二甲硅基三氟甲磺酸酯
2-甲基噻唑-4-甲酸乙酯
(5S)-5-(tert-butyl-dimethyl-silanyloxy)-4,4-dimethyloct-7en-3-one
1-{1-[(1E)-1-methyl-2-(2-methyl(1,3-thiazol-4-yl))vinyl](1S)(3Z)-4-methylhepta-3,6-dienyloxy}-1,1,2,2-tetramethyl-1-silapropane
(3S,6R,7S,8S,12Z,15S,16E)-1,3,15-三-{[叔-丁基(二甲基)硅烷基]氧基}-7-羟基-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)十七烷基-12,16-二烯-5-酮
(3S)-2-methyl-1-(2-methyl-1,3-thiazol-4-yl)hexa-1,5-dien-3-ol
(2S,6Z,9S,10E)-9-((tert-butyldimethylsilyl)oxy)-N-((S)-2-(methoxymethyl)pyrrolidin-1-yl)-2,6,10-trimethyl-11-(2-methylthiazol-4-yl)undeca-6,10-dien-1-imine
(2E,6E)(5S)-6-methyl-7-(2-methyl-(1,3-thiazol-4-yl))-2-prop-2-enyl-5-(1,1,2,2-tetramethyl-1-silapropoxy)hepta-2,6-dien-1-ol
(+)-(2S,6Z,9S,10E)-9-{[叔-丁基(二甲基)硅烷基]氧基}-2,6,10-三甲基-11-(2-甲基-1,3-噻唑-4-基)-十一碳-6,10-二烯-1-醇
(-)-(2Z,5S,6E)-5-{[叔-丁基(二甲基)硅烷基]氧基}-2,6-二甲基-7-(2-甲基-1,3-噻唑-4-基)庚-2,6-二烯-1-醇
(3S)-3-{[叔-丁基(二甲基)硅烷基]氧基}-5-羟基戊烷-2-酮
4-[(1E,3S,5Z,8R/S,10S)-3,11-二-{[叔-丁基(二甲基)硅烷基]氧基}-2,6,10-三甲基-8-(苯磺酰基)十一碳-1,5-二烯基]-2-甲基-1,3-噻唑
4-((S,1E,5Z)-3-((tert-butyldimethylsilyl)oxy)-9-iodo-2,6-dimethylnona-1,5-dien-1-yl)-2-methylthiazole
(4S)-4,6-二-{[叔-丁基二甲基硅烷基)氧基]}-3,3-二甲基己烷-2-酮
(S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-pentanoic acid phenyl ester
(5S)-5,7-二-{[叔-丁基二甲基硅烷基)氧基]}-4,4-二甲基庚烷-3-酮
叔丁基二甲基氯硅烷
(-)-(3S,4E)-3-{[叔-丁基(二甲基)硅烷基]氧基}-4-甲基-5-(2-甲基-1,3-噻唑-4-基)戊-4-烯-1-醇
(3S)-4-{[叔-丁基(二甲基)硅烷基]氧基}-3-甲基丁基苯基砜
(S)-4-benzyl-3-((2S,6E,9S,10E)-9-((tert-butyldimethylsilyl)oxy)-6-(chloromethyl)-2,10-dimethyl-11-(2-methylthiazol-4-yl)undeca-6,10-dienoyl)oxazolidin-2-one
(S)-4-benzyl-3-((S)-6-iodo-2-methylhept-6-enoyl)oxazolidin-2-one
(4S)-4-benzyl-3-((2S,9S,E)-9-((tert-butyldimethylsilyl)oxy)-7-hydroxy-2,10-dimethyl-6-methylene-11-(2-methylthiazol-4-yl)undec-10-enoyl)oxazolidin-2-one
(-)-(5S)-5,7-bis(tert-butyldimethylsilyloxy)-4,4-dimethylheptan-3-ol
3-[(叔丁基二甲基甲硅烷基)氧基]-1-丙醇
乙基(2Z,5S,6E)-5-{[叔-丁基(二甲基)硅烷基]氧基}-2,6-二甲基-7-(2-甲基-1,3-噻唑-4-基)庚-2,6-二烯酸酯
(3S,4E)-3-{[tert-butyl(dimethyl)silyl]oxy}-4-methyl-5-(2-methyl-1,3-thiazol-4-yl)pent-4-en-1-al
(-)-(3S)-3-{[叔-丁基(二甲基)硅烷基]氧基}二氢呋喃-2(3H)-酮
(4S,6E)-4-(tert-butyldimethylsilanyloxy)-5-methyl-6-(2-methyl-1,3-thiazol-4-yl)-5-hexene-1,2-diol
4-[(1E,3S,5Z,8R/S,10S)-3,11-二-{[叔-丁基(二甲基)硅烷基]氧基}-2,6,10-三甲基-十一碳-1,5-二烯基]-2-甲基-1,3-噻唑
下游产品
(3S,6R,7S,8S,12Z,15S,16E)-3,7,15-三-{[叔-丁基(二甲基)硅烷基]氧基}-4,4,6,8,12,16-六甲基-17-(2-甲基-1,3-噻唑-4-基)-5-氧代-十七-12,16-二烯酸
埃博霉素B
Epothilone D