化合物简介
27-Hydroxycholesterol (27-HC) is an endogenous oxysterol with multiple biological functions, including activity as a selective estrogen receptor modulator (SERM) (a mixed, tissue-specific agonist-antagonist of the estrogen receptor (ER)) and as an agonist of the liver X receptor (LXR). It is a metabolite of cholesterol that is produced by the enzyme CYP27A1.
基本信息
中文名称
5,25R-胆甾烯-3beta,26-二醇
英文名称
(25R)-cholest-5-ene-3β,26-diol
中文别名
27-羟基胆固醇
英文别名
5,25R-Cholesten-3beta,26-diol、(25R)-cholest-5-ene-3beta,26-diol
CAS号
20380-11-4
分子式
C27H46O2
分子量
402.653
精确质量
402.35
PSA
40.46
LOGP
6.3611
编号系统
UNII
6T2NA6P5SQ
物化性质
密度
1.03
沸点
517.1ºC at 760 mmHg
熔点
172 - 173 °C
闪点
215.6ºC
折射率
1.537
蒸汽压
7.43E-13mmHg at 25°C
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