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磷酸奥司他韦

磷酸奥司他韦

CAS号：204255-11-8

英文名：oseltamivir phosphate

分子式

C16H31N2O8P

熔点

密度

1.08g/cm3

分子量

410.4

沸点

473.3ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Orally active inhibitor of influenza virus neuraminidase; converted in vivo to the active acid metabolite. An antiviral drug.

基本信息

中文名称

磷酸奥司他韦

英文名称

oseltamivir phosphate

中文别名

(3R,4R,5S)-4-乙酰胺基-5-氨基-3-(1-乙基丙氧基)-1-环己烯-1-羧酸乙酯磷酸盐、达菲/磷酸奥司他韦

英文别名

OseltaMivir Acid-D3 Phosphate、Osteltamivir phosphate、Oseltamir phosphate、Oseltamivir phosphate、Oseltamivir phosphat、Oseltamivir Phosphate、NTERMEDIATES OF OSELTAMIVIR、Oselt

CAS号

204255-11-8

分子式

C16H31N2O8P

分子量

410.4

精确质量

410.182

PSA

178.22

LOGP

1.448

编号系统

MDL号

MFCD17676100

物化性质

外观与性状

白色水晶般的固体

密度

1.08g/cm3

沸点

473.3ºC at 760 mmHg

闪点

240ºC

安全信息

海关编码

2942000000

合成路线

共找到1条合成路线 >

奥司他韦

磷酸奥司他韦

磷酸奥司他韦

海关数据

共找到8个国家海关数据 >

国家/地区名称	海关编码	更新时间	操作
中国	2924299090	2019-03	查看
美国	2924299500	2019-03	查看
印度	29242990	2019-03	查看
欧盟	29242998	2019-03	查看
英国	2924299899	2019-03	查看
日本	292429090	2019-03	查看
韩国	2924299090	2019-03	查看
加拿大	2924290090	2019-03	查看

上游原料

共找到89个上游原料 >

(1R,5R,6R)-5-(1-乙丙基)-7-氮杂双环[4.1.0]庚-3-烯-3-羧酸乙酯

(1R,5R,6R)-5-(1-乙丙基)-7-氮杂双环[4.1.0]庚-3-烯-3-羧酸乙酯

(R)-1-((3aS,4R,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethane-1,2-diol

(R)-1-((3aS,4R,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethane-1,2-diol

奥司他韦

2,3:5,6-di-O-isopentylidene-α-D-mannofuranose

2,3:5,6-di-O-isopentylidene-α-D-mannofuranose

5-叠氮奥塞米韦

5-叠氮奥塞米韦

ethyl (1S,5R,6S)-7-(tert-butoxycarbonyl)-5-(methanesulfonyloxy)-7-azabicyclo[4.1.0]hept-2-ene-3-carboxylate

ethyl (1S,5R,6S)-7-(tert-butoxycarbonyl)-5-(methanesulfonyloxy)-7-azabicyclo[4.1.0]hept-2-ene-3-carboxylate

下游产品

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奥司他韦

上游原料

(1R,5R,6R)-5-(1-乙丙基)-7-氮杂双环[4.1.0]庚-3-烯-3-羧酸乙酯 (R)-1-((3aS,4R,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)ethane-1,2-diol 奥司他韦 2,3:5,6-di-O-isopentylidene-α-D-mannofuranose 5-叠氮奥塞米韦 ethyl (1S,5R,6S)-7-(tert-butoxycarbonyl)-5-(methanesulfonyloxy)-7-azabicyclo[4.1.0]hept-2-ene-3-carboxylate (2R,3S)-tert-butyl 2-((tert-butyldimethylsilyloxy)methyl)-3-((R)-3-(ethoxycarbonyl)-1-hydroxybut-3-en-1-yl)aziridine-1-carboxylate (2R,3S)-1-tert-butyl 2-((tert-butyldimethylsilyloxy)methyl)-3-((R)-3-(ethoxycarbonyl)-1-(methanesulfonyloxy)but-3-en-1-yl)-aziridine-1-carboxylate (3R,4S,5R)-4-acetylamino-3-(1-ethyl-propoxy)-5-methanesulfonyloxy-cyclohex-1-enecarboxylic acid ethyl ester oseltamivir (1R,5S)-ethyl 5-(N-(tert-butoxycarbonyl)-4-nitrophenylsulfonamido)cyclohex-3-enecarboxylate N-(4-chloro-7-oxo-6-oxabicyclo[3.2.1]octan-3-yl)acetamide 3,4-O-(二乙基甲基亚基)莽草酸乙酯 ethyl 3,4-O-isopropylidene-5-O-(methansulfonyl)shikimate 3-Cyclohexene-1-carboxylic acid (S)-pantolactone ester (2R,3S,4S,5S)-5-(benzyloxy)-2-(hydroxymethyl)-4-(pentan-3-yloxy)tetrahydrofuran-3-ol (1S,3S,4R,5R)-ethyl 4-azido-3-(tert-butoxycarbonylamino)-5-hydroxycyclohexanecarboxylate 莽草酸乙酯磷酸 (1S,3S,4S,5S)-ethyl-3-azido-5-(tert-butoxycarbonylamino)-4-(trimethylsilyloxy)cyclohexanecarboxylate ((3aS,4R,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl acetate (1S,3S,4S,5S)-ethyl 3-azido-5-(tert-butoxycarbonylamino)-4-hydroxycyclohexanecarboxylate (3S,4S,5S)-ethyl-3-azido-5-(tert-butoxycarbonylamino)-4-hydroxy-1-(phenylselanyl)cyclohexanecarboxylate (3aS,4S,6R,6aS)-4-(benzyloxy)-6-((R)-2,2-diethyl-1,3-dioxolan-4-yl)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxole (1S,5S,6S)-ethyl 5-(tert-butoxycarbonylamino)-7-azabicyclo[4.1.0]hept-3-ene-3-carboxylate 莽草酸 tert-butyl (2S,3R)-2-((R)-3-(ethoxycarbonyl)-1-((methylsulfonyl)oxy)but-3-en-1-yl)-3-(hydroxymethyl)aziridine-1-carboxylate ethyl (3R,4R,5R)-4-acetamido-3-(1-ethyl-propoxy)-5-hydroxy-cyclohex-1-ene-1-carboxylate (3R,4R,5S)-4-azido-5-tert-butoxycarbonylamino-3-(1-ethylpropoxy)cyclohex-1-enecarboxylic acid ethyl ester (((2S,3R,4S,5S)-3-azido-5-(benzyloxy)-4-(pentan-3-yloxy)tetrahydrofuran-2-yl)methoxy)(tert-butyl)dimethylsilane (1R,5S)-ethyl 5-(tert-butoxycarbonylamino)cyclohex-3-enecarboxylate (1R,5R)-ethyl 5-hydroxycyclohex-3-enecarboxylate (3R,4S,5R)-4-amino-3-(1-ethyl-propoxy)-5-methanesulfonyloxy-cyclohex-1-enecarboxylic acid ethyl ester ethyl (3aR,7R,7aR)-2,2-dimethyl-7-methanesulfonyloxy-3a,6,7,7a-tetrahydrobenzo[1,3]dioxole-5-carboxylate (R)-3-环己烯甲酸 (1R,3S,5S,6S)-ethyl 5-(tert-butoxycarbonylamino)-7-oxabicyclo[4.1.0]heptane-3-carboxylate (((3aS,4R,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methoxy)trimethylsilane (1S,3S,4R,5R)-ethyl 4-azido-3-(tert-butoxycarbonylamino)-5-(trimethylsilyloxy)cyclohexanecarboxylate 5-(戊烷-3-基氧基)-7-氧代-双环[4.1.0]庚-3-烯-3-羧酸乙酯 (2S,3R)-tert-butyl 2-((R)-3-(ethoxycarbonyl)-1-(methanesulfonyloxy)but-3-en-1-yl)-3-formylaziridine-1-carboxylate (1R,2R,5R)-2-iodo-7-oxabicyclo[3.2.1]octan-6-one (3R,4R,5S)-ethyl-4-azido-5-(tert-butoxycarbonylamino)-3-hydroxycyclohex-1-enecarboxylate (3aS,4S,6S,6aS)-6-(benzyloxy)-2,2-diethyltetrahydrofuro[3,4-d][1,3]dioxole-4-carbaldehyde N-脱乙酰基5-叠氮基奥塞米韦

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