化合物简介
4-Methylthiazole-5-carboxylic acid is used as a reagent to synthesize thiazolylimidazolidinone compounds that act as Stearoyl-CoA desaturase-1 (SCD1) inhibitors. These SCD1 inhibitors are used in the treatment of metabolic diseases. 4-Methylthiazole-5-carboxylic acid is also used as a reagent to synthesize 4-Methyl-5-formylthiazole, an important intermediate in the synthesis of Cefditoren pivoxil.
基本信息
中文名称
4-甲基噻唑-5-甲酸
英文名称
4-methyl-1,3-thiazole-5-carboxylic acid
中文别名
4-甲基-1,3-噻唑-5-羧酸、4-甲基-1H-噻唑-5-羧酸、4-甲基-5-噻唑甲酸
英文别名
4-methyl-1,3-thiadiazole-5-carboxylic acid、4-Methyl-1H-thiazole-5-carboxylic acid、4-Methyl-thiazol-5-carbonsaeure、4-Methyl-5-thiazolecarboxylic acid、4-Methyl-1,3-thiazole-5-carboxylic acid、4-Methylthiazole-5-carboxylic acid、4-methylthiazole-5-carboxylicacid、5-Thiazolecarboxylic acid, 4-methyl-、4-Methyl-thiazole-5-carboxylic acid、5-Thiazolecarboxylic acid,4-methyl
CAS号
20485-41-0
分子式
C5H5NO2S
分子量
143.164
精确质量
143.004
PSA
78.43
LOGP
1.1497
编号系统
MDL号
MFCD00626872
PubChem号
24882570
物化性质
外观与性状
白色至淡黄色晶体粉末
密度
1.418 g/cm3
沸点
303.6ºC at 760 mmHg
熔点
287°C (dec.)(lit.)
闪点
137.4ºC
折射率
1.611
稳定性
Stable at normal temperratures and pressures.
储存条件
Keep container tightly closed.
蒸汽压
0.003mmHg at 25°C
安全信息
RTECS号
XJ3680000
安全说明
S37/39-S26
WGK Germany
3
危险类别码
R36/37/38
海关编码
2934100090
危险品标志
Xi
危险标志
GHS07
危险性描述
H317
危险性防范说明
P280
信号词
Warning
生产方法及用途
用途
用作医药中间体
海关数据
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