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(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
CAS号:204918-13-8
英文名:(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
分子式:C40H71NO5SSi2
分子量:734.231
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合成路线
204917-57-7
(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-59-9
4-[(1E,5Z)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-11-iodo-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-70-4
(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienenitrile
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-72-6
(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienal
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-64-6
[(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dien-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-97-5
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-99-7
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-5-oxo-nonadeca-14,18-dienal
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204918-05-8
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-5-oxo-nonadeca-14,18-dienoic acid
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-90-8
(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,7,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
204917-85-1
(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,17-Tris-(tert-butyl-dimethyl-silanyloxy)-7-hydroxy-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
204918-13-8
(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione
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上游原料
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-1-hydroxy-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienal
[(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dien-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-5-oxo-nonadeca-14,18-dienal
4-[(1E,5Z)-(S)-3,11-Bis-(tert-butyl-dimethyl-silanyloxy)-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-17-hydroxy-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-5-oxo-nonadeca-14,18-dienoic acid
(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol
(14Z,18E)-(3S,6R,7S,8S,17S)-3,7,17-Tris-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-5-oxo-nonadeca-14,18-dienoic acid
4-[(1E,5Z)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-11-iodo-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole
(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,7,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,17-Tris-(tert-butyl-dimethyl-silanyloxy)-7-hydroxy-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one
(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienenitrile
下游产品
Epothilone I1