百科

Epothilone I1

Epothilone I1

CAS号：204918-15-0

英文名：Epothilone I1

分子式

C28H43NO5S

熔点

密度

分子量

505.71

沸点

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

基本信息

中文名称

Epothilone I1

英文名称

Epothilone I1

中文别名

英文别名

(Z)-(4S,7R,8S,9S,18S)-4,8-Dihydroxy-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione

CAS号

204918-15-0

分子式

C28H43NO5S

分子量

505.71

精确质量

505.286

PSA

124.96

LOGP

5.6564

合成路线

(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol

(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol

Epothilone I1

上游原料

共找到6个上游原料 >

(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienal

(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienal

[(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dien-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

[(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dien-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine

(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol

(6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol

(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione

(Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione

4-[(1E,5Z)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-11-iodo-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole

4-[(1E,5Z)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-11-iodo-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole

(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,7,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one

(14Z,18E)-(3S,6R,7S,8S,17S)-1,3,7,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one

上游原料

(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dienal [(8Z,12E)-(2S,11S)-11-(tert-Butyl-dimethyl-silanyloxy)-2,12-dimethyl-13-(2-methyl-thiazol-4-yl)-trideca-8,12-dien-(E)-ylidene]-((S)-2-methoxymethyl-pyrrolidin-1-yl)-amine (6Z,10E)-(S)-9-(tert-Butyl-dimethyl-silanyloxy)-10-methyl-11-(2-methyl-thiazol-4-yl)-undeca-6,10-dien-1-ol (Z)-(4S,7R,8S,9S,18S)-4,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5,5,7,9-tetramethyl-18-[(E)-1-methyl-2-(2-methyl-thiazol-4-yl)-vinyl]-oxacyclooctadec-15-ene-2,6-dione 4-[(1E,5Z)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-11-iodo-2-methyl-undeca-1,5-dienyl]-2-methyl-thiazole (14Z,18E)-(3S,6R,7S,8S,17S)-1,3,7,17-Tetrakis-(tert-butyl-dimethyl-silanyloxy)-4,4,6,8,18-pentamethyl-19-(2-methyl-thiazol-4-yl)-nonadeca-14,18-dien-5-one