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25-羟基胆甾醇

25-羟基胆甾醇

CAS号：2140-46-7

英文名：25-hydroxycholesterol

分子式

C27H46O2

熔点

密度

1.03g/cm3

分子量

402.653

沸点

513.1ºC at 760mmHg

溶解度

信号词

Warning

危险品标志

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化合物简介

An oxygenated derivative of Cholesterol; an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.

基本信息

中文名称

25-羟基胆甾醇

英文名称

25-hydroxycholesterol

中文别名

5-胆甾烯-3β,25-二醇、5-胆甾烯-3Β,25-二醇、25-羟基胆固醇

英文别名

25-Hydroxy Cholesterol、(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

CAS号

2140-46-7

分子式

C27H46O2

分子量

402.653

精确质量

402.35

PSA

40.46

LOGP

6.5036

编号系统

BRN号

3161259

MDL号

3161259

物化性质

密度

1.03g/cm3

沸点

513.1ºC at 760mmHg

闪点

213.5ºC

折射率

1.538

蒸汽压

1.13E-12mmHg at 25°C

安全信息

安全说明

S26; S36; S45

危险类别码

R20/21/22; R36/37/38; R48

危险品标志

Xn

危险性描述

H302; H312; H315; H319; H332; H335; H373

危险性防范说明

P261; P280; P305 + P351 + P338

信号词

Warning

危险标志

GHS07, GHS08

合成路线

共找到3条合成路线 >

25-羟基胆甾-5-烯-3beta-基乙酸酯

25-羟基胆甾-5-烯-3beta-基乙酸酯

25-羟基胆甾醇

25-羟基胆甾醇

上游原料

共找到57个上游原料 >

25-羟基胆甾-5-烯-3beta-基乙酸酯

25-羟基胆甾-5-烯-3beta-基乙酸酯

ethyl (R)-5-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)hex-2-enoate

ethyl (R)-5-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)hex-2-enoate

3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-oic acid methyl ester

3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-oic acid methyl ester

(2S,Z)-2-((3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5-(methylthio)-5-(trimethylsilyl)pent-4-en-2-ol

(2S,Z)-2-((3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5-(methylthio)-5-(trimethylsilyl)pent-4-en-2-ol

(3b)-3-羟基-胆-5-烯-24-酸甲酯

(3b)-3-羟基-胆-5-烯-24-酸甲酯

(3beta)-3-[(四氢-2H-吡喃-2-基)氧基]-胆-5-烯-24-醛

(3beta)-3-[(四氢-2H-吡喃-2-基)氧基]-胆-5-烯-24-醛

下游产品

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25-羟基胆甾-5-烯-3beta-基乙酸酯

25-羟基胆甾-5-烯-3beta-基乙酸酯

25-氟胆固醇

25-氟胆固醇

上游原料

25-羟基胆甾-5-烯-3beta-基乙酸酯 ethyl (R)-5-((3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)hex-2-enoate 3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-oic acid methyl ester (2S,Z)-2-((3S,8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-((tetrahydro-2H-pyran-2-yl)oxy)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5-(methylthio)-5-(trimethylsilyl)pent-4-en-2-ol (3b)-3-羟基-胆-5-烯-24-酸甲酯 (3beta)-3-[(四氢-2H-吡喃-2-基)氧基]-胆-5-烯-24-醛 [17(20)Z]-pregna-5,17(20)-diene-3β,11α-diyl diacetate 5β-cholestane-3α,25-diol 25-(Tetrahydro-2H-pyran-2-yl)oxy-5-cholesten-3β-ol 3-β-acetyloxy-17-ethenylidenandrost-5-ene (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-oxoheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate 3β,11α-bis(methoxymethoxy)chol-5-en-24-ol 4-(benzenesulfonyl)-2-methylbutan-2-ol 3β,11α-dihydroxychol-5-en-24-oic acid 3β-(tert-butyldimethylsiloxy)cholest-5-en-25-ol (3β,20(22)E,23Z)-24-(methylthio)-3-[(tetrahydro-2H-pyran-2-yl)oxy]cholesta-5,20(22),23-trien-25-ol 3β-hydroxy-24-nor-chol-5-ene-23-nitrile cholesta-5,24-diene-3β,11α-diol 27-去甲-25-氧代胆固醇 3β-(tert-butyldimethylsiloxy)cholest-5-ene-11α,25-diol 17-(Z)-ethylidene-3β-hydroxy-5-androstene 3-((10R,13R)-3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-butyraldehyde methyl 3β,11α-diacetoxychol-5-en-24-oate cholest-5-ene-3β,25-diol 3-tetrahydropyran-2-yl ether (3S,8R,9S,10R,13S,14S)-17-((R,E)-6-hydroxy-6-methylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl acetate 4-(3-acetyloxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid 3B-羟基-D5-胆烯酸 (3β,20S,22E)-24-(methylthio)-3-[(tetrahydro-2H-pyran-2-yl)oxy]cholesta-5,22,24-trien-20-ol 3β,11α-dihydroxyandrost-5-en-17-one 3β-(tetrahydro-2H-pyran-2-yloxy)chol-5-en-24-ol desmosterol acetate (24S)-24,25-环氧胆固醇 (3S,8S,9S,10R,11R,13S,14S,Z)-17-ethylidene-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,11-diol 链甾醇 (25-(Tetrahydro-2H-pyran-2-yl)oxy-5-cholesten-3β-ol)-acetat 2-[(3beta)-胆甾-5,24-二烯-3-基氧基]四氢-2H-吡喃 4β-Brom-5β-cholestan-25-ol-3-on methyl (22E)-3β,11α-diacetoxychola-5,16,22-trien-24-oate 2-[4-(benzenesulfonyl)-2-methylbutan-2-yl]oxyoxane 2-甲基-4-戊炔-2-醇 2-(((3S,8S,9S,10R,13R,14S,17R)-17-((R)-5-bromopentan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)tetrahydro-2H-pyran O-[3β-(tert-butyldimethylsiloxy)-25-hydroxycholest-5-en-11α-yl] imidazole-1-carbothioate 去氢表雄酮 3β,11α-bis(methoxymethoxy)cholesta-5,24-diene 3β,11α-bis(methoxymethoxy)chol-5-en-24-al magnesium,carbanide,iodide cholest-5-ene-3β,11α,25-triol 6β-Methoxy-25-<(tetrahydropyran-2yl)oxy>-3β,5-cyclo-5α-cholestan

下游产品

25-羟基胆甾-5-烯-3beta-基乙酸酯 25-氟胆固醇