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N-硬脂酰神经鞘氨醇

N-硬脂酰神经鞘氨醇

CAS号：2304-81-6

英文名：C18 CERAMIDE

分子式

C36H71NO3

熔点

99 - 101ºC

密度

0.915g/cm3

分子量

565.954

沸点

694.5ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

The sphingolipid ceramide is a potent inhibitor of the mitochondrial permeability transition pore.

基本信息

中文名称

N-硬脂酰神经鞘氨醇

英文名称

C18 CERAMIDE

中文别名

(2R,3R,4E)-硬脂酰鞘氨醇

英文别名

STEAROYL CERAMIDE、ceramide c18、N-Stearoyl-D-erythro-sphingosine、N-stearoylsphingosine、Cer(d18:1/18:0)、N-((2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide、N-STEAROYLSPHINGANINE、C18 DIHYDROCERAMIDE、N-(octadecanoyl)-sphing-4-enine、N-18:0 SPHINGANINE、N-stearoyl-D-erythro-sphingosine、C18-D-ERYTHRO-CERAMIDE、N-Stearoyl-D-sphingosine、18:0 CERAMIDE、N-((2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl)stearamide、(2S,3R,4E)-2-(N-stearoylamino)-4-octadecene-1,3-diol、N-STEAROYL CERAMIDE

CAS号

2304-81-6

分子式

C36H71NO3

分子量

565.954

精确质量

565.543

PSA

69.56

LOGP

10.7341

物化性质

外观与性状

白色粉末

密度

0.915g/cm3

沸点

694.5ºC at 760 mmHg

熔点

99 - 101ºC

闪点

373.8ºC

折射率

1.479

稳定性

Stable, but may be heat sensitive - store below 4ºC. Incompatible with strong oxidizing agents.

储存条件

-20ºC

蒸汽压

2.59E-22mmHg at 25°C

安全信息

安全说明

S24/25

合成路线

共找到9条合成路线 >

(2S,3R,4E)-3-(benzyloxymethoxy)-1-(tert-butyldimethylsiloxy)-2-(octadecanoylamino)-4-octadecene

(2S,3R,4E)-3-(benzyloxymethoxy)-1-(tert-butyldimethylsiloxy)-2-(octadecanoylamino)-4-octadecene

N-硬脂酰神经鞘氨醇

N-硬脂酰神经鞘氨醇

上游原料

共找到4个上游原料 >

(2S,3R,4E)-3-(benzyloxymethoxy)-1-(tert-butyldimethylsiloxy)-2-(octadecanoylamino)-4-octadecene

(2S,3R,4E)-3-(benzyloxymethoxy)-1-(tert-butyldimethylsiloxy)-2-(octadecanoylamino)-4-octadecene

<2(S),3(R),4E>-2-amino-1,3-O-isopropylidene-4-octadecene-1,3-diol

<2(S),3(R),4E>-2-amino-1,3-O-isopropylidene-4-octadecene-1,3-diol

下游产品

共找到8个下游商品 >

(1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-15-((4-methoxybenzyl)oxy)-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecan-16-yl benzoate

(1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-15-((4-methoxybenzyl)oxy)-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecan-16-yl benzoate

(2S,3R,4E)-3-O-benzoyl-2-octadecanamido-4-octadecene-1,3-diol

(2S,3R,4E)-3-O-benzoyl-2-octadecanamido-4-octadecene-1,3-diol

(1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecane-15,16-diyl diacetate

(1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecane-15,16-diyl diacetate

(2S,3R,4E)-1-O-(α-D-glucopyranosyl)-2-(N-octadecanosylamino)octadec-4-ene-1,3-diol

(2S,3R,4E)-1-O-(α-D-glucopyranosyl)-2-(N-octadecanosylamino)octadec-4-ene-1,3-diol

3-O-benzoyl-1-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-N-stearoyl-D-erythro-sphingosine

3-O-benzoyl-1-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-N-stearoyl-D-erythro-sphingosine

(2S,3R,4E)-1-O-tert-butyldimethylsilyl-3-O-succinoyl-2-octadecanamido-4-octadecene-1,3-diol

(2S,3R,4E)-1-O-tert-butyldimethylsilyl-3-O-succinoyl-2-octadecanamido-4-octadecene-1,3-diol

上游原料

(2S,3R,4E)-3-(benzyloxymethoxy)-1-(tert-butyldimethylsiloxy)-2-(octadecanoylamino)-4-octadecene <2(S),3(R),4E>-2-amino-1,3-O-isopropylidene-4-octadecene-1,3-diol

下游产品

(1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-15-((4-methoxybenzyl)oxy)-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecan-16-yl benzoate (2S,3R,4E)-3-O-benzoyl-2-octadecanamido-4-octadecene-1,3-diol (1R,4S,5R,13R,14R,15S,16R)-14-hydroxy-7,10-dioxo-5-((E)-pentadec-1-en-1-yl)-4-stearamido-2,6,11,17-tetraoxabicyclo[11.3.1]heptadecane-15,16-diyl diacetate (2S,3R,4E)-1-O-(α-D-glucopyranosyl)-2-(N-octadecanosylamino)octadec-4-ene-1,3-diol 3-O-benzoyl-1-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-N-stearoyl-D-erythro-sphingosine (2S,3R,4E)-1-O-tert-butyldimethylsilyl-3-O-succinoyl-2-octadecanamido-4-octadecene-1,3-diol ((2R,3R,4S,5R,6S)-5-(benzoyloxy)-3-hydroxy-4-((4-methoxybenzyl)oxy)-6-(phenylthio)tetrahydro-2H-pyran-2-yl)methyl ((2S,3R,E)-1-((tert-butyldimethylsilyl)oxy)-2-stearamidooctadec-4-en-3-yl) succinate ((2R,3R,4S,5R,6S)-5-(benzoyloxy)-3-hydroxy-4-((4-methoxybenzyl)oxy)-6-(phenylthio)tetrahydro-2H-pyran-2-yl)methyl ((2S,3R,E)-1-hydroxy-2-stearamidooctadec-4-en-3-yl) succinate