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辅酶Q8

辅酶Q8

CAS号：2394-68-5

英文名：ubiquinone-8

分子式

C49H74O4

熔点

密度

0.97g/cm3

分子量

727.109

沸点

782.9ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

An isoprenoid quinone that enhances nonspecific resistance to bacterial infections. It stimulates phagocytosis in macrophages by modulation of the kinetics of the Fc receptor. It serves as an electron carrier from the flavoprotein to the cytochrome complex in reconstituted proteoliposomes where cytochrome O complex function as an efficient ubiquinol-8 oxidase.

基本信息

中文名称

辅酶Q8

英文名称

ubiquinone-8

中文别名

英文别名

2,3-dimethoxy-5-methyl-6-[(2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaenyl]cyclohexa-2,5-diene-1,4-dione、COQ8、Coenzyme Q8 (E. coli)、ubiquinone-40、oxidized coenzyme Q8、Ubiquinone Q8、Coenzyme Q8

CAS号

2394-68-5

分子式

C49H74O4

分子量

727.109

精确质量

726.559

PSA

52.6

LOGP

14.4009

编号系统

UNII

CQA993F7P8

物化性质

密度

0.97g/cm3

沸点

782.9ºC at 760mmHg

闪点

303.2ºC

合成路线

三甲基铝

2-chloromethyl-5,6-dimethoxy-3-methyl-[1,4]benzoquinone

2-chloromethyl-5,6-dimethoxy-3-methyl-[1,4]benzoquinone

(5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-Heptamethyl-hentriaconta-5,9,13,17,21,25,29-heptaen-1-yne

(5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-Heptamethyl-hentriaconta-5,9,13,17,21,25,29-heptaen-1-yne

辅酶Q8

上游原料

共找到35个上游原料 >

((5E,9E)-11-Chloro-6,10-dimethyl-undeca-5,9-dien-1-ynyl)-trimethyl-silane

((5E,9E)-11-Chloro-6,10-dimethyl-undeca-5,9-dien-1-ynyl)-trimethyl-silane

farnesylgeranyl chloride

farnesylgeranyl chloride

(2E,6E)-2,6-dimethyl-4-tosyl-11-(trimethylsilyl)undeca-2,6-dien-10-yn-1-ol

(2E,6E)-2,6-dimethyl-4-tosyl-11-(trimethylsilyl)undeca-2,6-dien-10-yn-1-ol

geranylfarnesol

geranylfarnesol

(2E,6E,10E,14E)-3,7,11,15,19-pentamethyl-5-tosylicosa-2,6,10,14,18-pentaen-1-ol

(2E,6E,10E,14E)-3,7,11,15,19-pentamethyl-5-tosylicosa-2,6,10,14,18-pentaen-1-ol

三甲基铝

上游原料

((5E,9E)-11-Chloro-6,10-dimethyl-undeca-5,9-dien-1-ynyl)-trimethyl-silane farnesylgeranyl chloride (2E,6E)-2,6-dimethyl-4-tosyl-11-(trimethylsilyl)undeca-2,6-dien-10-yn-1-ol geranylfarnesol (2E,6E,10E,14E)-3,7,11,15,19-pentamethyl-5-tosylicosa-2,6,10,14,18-pentaen-1-ol 三甲基铝 (((2-((2E,6E,10E,14E,18E,22E,26E)-28-chloro-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl)-5,6-dimethoxy-3-methyl-1,4-phenylene)bis(oxy))bis(methylene))dibenzene (6E,10E,14E,18E,22E,26E)-28-(2,5-bis(benzyloxy)-3,4-dimethoxy-6-methylphenyl)-2,6,10,14,18,22,26-heptamethyloctacosa-1,6,10,14,18,22,26-heptaen-3-ol (E)-2-((4-chloro-3-methylbut-2-en-1-yl)oxy)tetrahydro-2H-pyran trans-3-hydroxymethyl-2-butenyl chloride (6E,10E,14E,18E,22E,26E)-28-(2,5-bis(benzyloxy)-3,4-dimethoxy-6-methylphenyl)-2-hydroxy-2,6,10,14,18,22,26-heptamethyloctacosa-6,10,14,18,22,26-hexaen-3-yl acetate 3-((3E,7E,11E,15E,19E,23E)-25-(2,5-bis(benzyloxy)-3,4-dimethoxy-6-methylphenyl)-3,7,11,15,19,23-hexamethylpentacosa-3,7,11,15,19,23-hexaen-1-yl)-2,2-dimethyloxirane 1-methyl-4-(((2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl)sulfonyl)benzene (E,E,E,E)-3,7,11,15,19-pentamethyl-1-(p-toluenesulfonyl)eicosa-2,6,10,14,18-pentaene 1,1-dimethoxy-2-methylbut-3-en-2-ol (6E,10E,14E,18E,22E,26E)-28-(2,5-bis(benzyloxy)-3,4-dimethoxy-6-methylphenyl)-2,6,10,14,18,22,26-heptamethyloctacosa-1,6,10,14,18,22,26-heptaen-3-yl acetate ((5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-heptamethylhentriaconta-5,9,13,17,21,25,29-heptaen-1-yn-1-yl)trimethylsilane E-1-chloro-2-methyl-7-trimethylsilyl-2-buten-6-yne E-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-al (2E)-4-氯-3-甲基-2-丁烯-1-醇 2,3-二甲氧基-5-甲基-1,4-苯醌 (((2,3-dimethoxy-5-methyl-6-((2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyl-29-tosyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl)-1,4-phenylene)bis(oxy))bis(methylene))dibenzene 1-chloro-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraene 1-溴-3-甲基-2-丁烯 1-methyl-4-(3-methylbut-2-enylsulfonyl)benzene Z-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-ol trimethyl((2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl)stannane 2-chloromethyl-5,6-dimethoxy-3-methyl-[1,4]benzoquinone E-2-methyl-7-trimethylsilyl-2-buten-6-yn-1-ol (5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-Heptamethyl-hentriaconta-5,9,13,17,21,25,29-heptaen-1-yne [(5E,9E,13E,17E,21E,25E)-6,10,14,18,22,26,30-Heptamethyl-12-(toluene-4-sulfonyl)-hentriaconta-5,9,13,17,21,25,29-heptaen-1-ynyl]-trimethyl-silane 一氧化异戊二烯 4-chloro-2-methyl-crotonaldehyde