化合物简介
7-Amino-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid is a cephalosporin derivative with antibacterial activity. 7-Amino-3-(1-methyl-5-tetrazolylthio)methyl-3-cephem-4-carboxylic Acid is an intermediate in the preparation of Cefmetazole and other semi-synthetic antibiotics.
基本信息
中文名称
7-氨基-3-(1-甲基-1H-四唑-5-硫代甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸
英文名称
7-Amino-3-(1-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
中文别名
7-氨基-3-(1-甲基-1-吡咯烷鎓基)甲基-2-头孢烯-2-羧酸盐酸盐、3-(1-甲基-1H-四氮唑-5-基)硫甲基-7-氨基头孢霉烷酸、(6R,反式)7-氨基-3-[(1-甲基-1H-四氮唑-5-基)硫]甲基-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯羧酸、7-TMCA(7-ACT)、7-氨基-3-(1-甲基-1H-四唑-5-硫甲基)-3-头孢烯-4-羧酸、头孢甲肟中间体(7-TMCA)、头孢甲肟中间体、头孢甲肟母核
英文别名
7-amino-2-carboxy-3-[(1-methyl-1,2,3,4-tetrazol-5-yl)-thiomethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene、(6R-trans)-7-amino-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid、7-Amino-3-[(1-methyltetrazol-5-yl)-thiomethyl]-cephalosporanic acid、3-(1-Methyl-1H-tetra-zolyl)thiomethyl-7-aminocephalosporanicacid、(6R)-7t-amino-3-(1-methyl-1H-tetrazol-5-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid、7-AMino-3-Methyl tetrazolyl cephalosporanic acid、7-Amino-3-methyl tetrazolyl cephalosporanic acid (7-TMCA)、7-amino-3-[[(1-methyltetrazol-5-yl)-thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid、7-ACA-3-MMT、7-TMCA、3-[[(1-Methyl-1H-tetrazol-5-yl)thio]methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-ene-2-carboxylic acid、3-[(1-methyltetrazol-5-ylthio)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid、7-AMINO-3-(1-METHYL-5-TETRAZOLYLTHIO)METHYL-3-CEPHEM-4-CARBOXYLIC ACID、7-Amino-3-(1-methylt、7-AMino-3-(cisopropyl-1-alkenyl)-3-epheM-4-arboxylic acid、7-amino-3-[[(1-methyl-1H-tetrazol-5-yl)-thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS号
24209-38-9
分子式
C10H12N6O3S2
分子量
328.371
精确质量
328.041
PSA
177.83
LOGP
-0.4785
编号系统
MDL号
MFCD23701403
物化性质
密度
5.67g/mLat 25°C(lit.)
沸点
695.2ºC at 760 mmHg
熔点
890°C
闪点
374.2ºC
折射率
1.956
蒸汽压
2.75E-20mmHg at 25°C
安全信息
安全说明
S20/21; S28; S45
WGK Germany
3
危险类别码
R23/25; R33; R50/53
危险品运输编码
UN 3283 6.1/PG 3
海关编码
2934999090
包装等级
III
危险品标志
T; N
生产方法及用途
用途
头孢哌酮、头孢羟唑的中间体。
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