化合物简介
Nomifensine (Merital, Alival) is a norepinephrine-dopamine reuptake inhibitor, i.e. a drug that increases the amount of synaptic norepinephrine and dopamine available to receptors by blocking the dopamine and norepinephrine reuptake transporters. This is a mechanism of action shared by some recreational drugs like cocaine and the medication Tametraline (see DRI). Research showed that the (S) isomer is responsible for activity.
基本信息
中文名称
诺米芬辛
英文名称
nomifensine
中文别名
苯异喹胺、2-甲基-4-苯基-8-氨基-1,2,3,4-四氢异喹啉
英文别名
2-Methyl-4-phenyl-1,2,3,4-tetrahydroisoquinolin-8-amine、Nomifenison、1,2,3,4-tetrahydro-8-amino-2-methyl-4-phenyl-isoquinolin、8-Amino-1,2,3,4-tetrahydro-2-methyl-4-phenylisoquinoline、linamiphen、Nomifensine Maleate、8-Isoquinolinamine,1,2,3,4-tetrahydro-2-methyl-4-phenyl、8-amino-4-phenyl-2-methyl-1,2,3,4-tetrahydro-isoquinoline、Nomifensine、8-Amino-2-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline、Nomifensin、1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamin、1,2,3,4-tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine
CAS号
24526-64-5
分子式
C16H18N2
分子量
238.328
精确质量
238.147
PSA
29.26
LOGP
3.3652
物化性质
密度
1.114g/cm3
沸点
378.4ºC at 760mmHg
闪点
164ºC
折射率
1.622
蒸汽压
6.28E-06mmHg at 25°C
安全信息
危险类别码
R22; R36/37/38
危险品运输编码
UN 3249
海关编码
2933499090
危险类别
6.1(b)
包装等级
III
危险品标志
Xn
上游原料
共找到12个上游原料 >下游产品
共找到5个下游商品 >