化合物简介
Amoscanate (INN), also known as nithiocyamine, is an experimental anthelmintic agent of the arylisothiocyanate class which was found to be highly effective in animals against the four major species of schistosomes which infect humans, and is also highly active against hookworm infection. However, significant liver toxicity was seen in lab animals at higher doses. The ether analogue of amoscanate, nitroscanate, is used in veterinary medicine as an anthelmintic.
基本信息
中文名称
4-硝基-4’-异硫氰基二苯胺
英文名称
amoscanate
中文别名
英文别名
4-Isothiocyanato-N-(4-nitrophenyl)aniline、4-(4-nitroanilino)-phenylisothiocyanate、4-Nitro-4\'-isothiocyano-diphenylamin、Amoscanato [INN-Spanish]、Ciba 9333 GO、4-Isothiocyanato-4\'-nitrodiphenylamine、4-(4-nitrophenyl)-aminophenylisothiocyanate、Amoscanate、Amoscanato、Amoscanatum、4-(4-Nitroanilino)phenylisothiocyanat、Nithiocyamine、Amoscanatum [INN-Latin]
CAS号
26328-53-0
分子式
C13H9N3O2S
分子量
271.294
精确质量
271.042
PSA
102.3
LOGP
4.6689
编号系统
UNII
X0MK46CVRB
物化性质
密度
1.3g/cm3
沸点
469.7ºC at 760mmHg
闪点
237.9ºC
折射率
1.654
储存条件
库房通风低温干燥
蒸汽压
5.38E-09mmHg at 25°C
安全信息
海关编码
2930909090