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3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

CAS号：263712-26-1

英文名：3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

分子式

C58H75N5O16Si

熔点

密度

分子量

1126.33

沸点

溶解度

信号词

危险品标志

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基本信息

中文名称

3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

英文名称

3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

中文别名

英文别名

CAS号

263712-26-1

分子式

C58H75N5O16Si

分子量

1126.33

精确质量

1125.5

PSA

248.19

LOGP

6.5814

合成路线

共找到5条合成路线 >

[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-acetic acid

[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-acetic acid

3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

3'-O-[(tert-butyl)dimethylsilyl]-2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

上游原料

共找到3个上游原料 >

5-(azidomethyl)-2'-deoxy-5'-O-pivaloyluridine

5-(azidomethyl)-2'-deoxy-5'-O-pivaloyluridine

[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-acetic acid

[(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-acetic acid

下游产品

共找到5个下游商品 >

2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine 3'-(S,S'-diphenyl phosphorodithioate)

2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine 3'-(S,S'-diphenyl phosphorodithioate)

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxy-3'-O-(tetrahdyro-2H-pyran-2-yl)uridine S-phenyl ester

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxy-3'-O-(tetrahdyro-2H-pyran-2-yl)uridine S-phenyl ester

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine S-phenyl ester

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine S-phenyl ester

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine 3'-(2-cyanoethyl diisopropylphosphoramidite) S-phenyl ester

{5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine 3'-(2-cyanoethyl diisopropylphosphoramidite) S-phenyl ester

2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine

上游原料

5-(azidomethyl)-2'-deoxy-5'-O-pivaloyluridine [(2R,3R,4R,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tert-butyl-dimethyl-silanyloxy)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-acetic acid

下游产品

2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine 3'-(S,S'-diphenyl phosphorodithioate) {5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxy-3'-O-(tetrahdyro-2H-pyran-2-yl)uridine S-phenyl ester {5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine S-phenyl ester {5:2'-O-[methyleneimino(2-oxoethane-2,1-diyl)]}-linked 5'-O-(4,4'-dimethoxytrityl)-P-thiouridyl-(3'->5')-2'-deoxyuridine 3'-(2-cyanoethyl diisopropylphosphoramidite) S-phenyl ester 2'-O-{2-{{{1-[2'-deoxy-5'-O-pivaloyl-3'-O-(tetrahydro-2H-pyran-2-yl)-β-D-ribofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl}methyl}amino}-2-oxoethyl}-5'-O-(4,4'-dimethoxytrityl)uridine