百科

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

CAS号：265666-24-8

英文名：(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

分子式：C38H61NO8Si

分子量：687.978

合成路线

657389-90-7

(3R)-2',2'-dimethyl-propionic acid 3-hydroxy-hex-5-ynyl ester

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

657389-63-4

(3S)-5-iodo-hex-5-ene-1,3-diol

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

657389-91-8

(3S)-3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-1-ol

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

657389-59-8

(3R)-2',2'-dimethyl-propionic acid 3-hydroxy-6-trimethylsilanyl-hex-5-ynyl ester

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

657389-60-1

(3R)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-hex-5-ynyl ester

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

657389-62-3

(3S)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-5-ynyl ester

265666-24-8

(2'R,4'R,6'R,4''R)-4-(2'',2''-dimethyl-[1'',3'']-dioxan-4''-ylmethyl)-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl}-pent-4-en-2-ol

上游原料

(3S)-5-iodo-hex-5-ene-1,3-diol (3S)-3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-1-ol (3R)-2',2'-dimethyl-propionic acid 3-hydroxy-hex-5-ynyl ester (3S)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-5-ynyl ester (3R)-2',2'-dimethyl-propionic acid 3-hydroxy-6-trimethylsilanyl-hex-5-ynyl ester (3R)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-hex-5-ynyl ester

下游产品

[4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-oxazol-2-yl]-methanol 4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxymethyl)-oxazole Methanesulfonic acid 4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-oxazol-2-ylmethyl ester