百科

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

CAS号：265666-25-9

英文名：(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

分子式：C36H59NO10SSi

分子量：726.005

合成路线

265666-23-7

(4S)-4-(2'-iodo-allyl)-2,2-dimethyl-[1,3]-dioxane

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-90-7

(3R)-2',2'-dimethyl-propionic acid 3-hydroxy-hex-5-ynyl ester

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-63-4

(3S)-5-iodo-hex-5-ene-1,3-diol

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-91-8

(3S)-3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-1-ol

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-59-8

(3R)-2',2'-dimethyl-propionic acid 3-hydroxy-6-trimethylsilanyl-hex-5-ynyl ester

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-60-1

(3R)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-hex-5-ynyl ester

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

657389-62-3

(3S)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-5-ynyl ester

265666-25-9

(2'S,4'R,6'R,5R)-methanesulfonic acid 5,7-dihydroxy-1-{6'-[2-(4-methoxybenzyloxymethyl)-oxazol-4-yl]-4'-(triisopropylsilanyloxy)-tetrahydropyran-2'-yl-methyl}-3-methyleneheptyl ester

上游原料

(3S)-5-iodo-hex-5-ene-1,3-diol (3S)-3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-1-ol (3R)-2',2'-dimethyl-propionic acid 3-hydroxy-hex-5-ynyl ester (3S)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-5-iodo-hex-5-ynyl ester (3R)-2',2'-dimethyl-propionic acid 3-hydroxy-6-trimethylsilanyl-hex-5-ynyl ester (4S)-4-(2'-iodo-allyl)-2,2-dimethyl-[1,3]-dioxane (3R)-2',2'-dimethyl-propionic acid 3-(tert-butyldimethylsilanyloxy)-hex-5-ynyl ester

下游产品

[4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-oxazol-2-yl]-methanol 4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxymethyl)-oxazole Methanesulfonic acid 4-((2R,4R,6R)-6-{(2R,6R)-6-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-4-triisopropylsilanyloxy-tetrahydro-pyran-2-yl)-oxazol-2-ylmethyl ester