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(S)-劳丹素

(S)-劳丹素

CAS号：2688-77-9

英文名：(S)-Laudanosine

分子式

C21H27NO4

熔点

密度

1.111g/cm3

分子量

357.443

沸点

468.1ºC at 760mmHg

溶解度

信号词

危险品标志

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化合物简介

Laudanosine or N-methyltetrahydropapaverine is a recognized metabolite of atracurium and cisatracurium. Laudanosine decreases the seizure threshold, and thus it can induce seizures if present at sufficient threshold concentrations; however such concentrations are unlikely to be produced consequent to chemodegradable metabolism of clinically administered doses of cisatracurium or atracurium.

基本信息

中文名称

(S)-劳丹素

英文名称

(S)-Laudanosine

中文别名

英文别名

Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-, (S)-、(1S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

CAS号

2688-77-9

分子式

C21H27NO4

分子量

357.443

精确质量

357.194

PSA

40.16

LOGP

3.4306

编号系统

EINECS号

220-253-2

物化性质

密度

1.111g/cm3

沸点

468.1ºC at 760mmHg

闪点

131.2ºC

合成路线

共找到2条合成路线 >

N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

(-)-8-苯基薄荷醇

(-)-8-苯基薄荷醇

(S)-劳丹素

(-)-laudanosine

(-)-laudanosine

上游原料

共找到47个上游原料 >

重氮甲烷

3,4-二甲氧基苯乙炔

3,4-二甲氧基苯乙炔

(E)-2-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)ethanamine

(E)-2-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)ethanamine

(E)-N-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)formamide

(E)-N-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)formamide

(S)-1-((3,4-Dimethoxyphenyl)methyl)-2-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

(S)-1-((3,4-Dimethoxyphenyl)methyl)-2-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

2-(2-((3,4-dimethoxyphenyl)ethynyl)-4,5-dimethoxyphenyl)ethan-1-amine

2-(2-((3,4-dimethoxyphenyl)ethynyl)-4,5-dimethoxyphenyl)ethan-1-amine

下游产品

共找到2个下游商品 >

3,4-二甲氧基苯甲醛

3,4-二甲氧基苯甲醛

2,3,6,7-tetramethoxy-9,10-dihydro-anthracene

2,3,6,7-tetramethoxy-9,10-dihydro-anthracene

上游原料

重氮甲烷 3,4-二甲氧基苯乙炔 (E)-2-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)ethanamine (E)-N-(2-(3,4-dimethoxystyryl)-4,5-dimethoxyphenyl)formamide (S)-1-((3,4-Dimethoxyphenyl)methyl)-2-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 2-(2-((3,4-dimethoxyphenyl)ethynyl)-4,5-dimethoxyphenyl)ethan-1-amine (E)-2-(3,4-dimethoxystyryl)-4,5-dimethoxybenzaldehyde (E)-4-(4,5-dimethoxy-2-((E)-2-nitrovinyl)styryl)-1,2-dimethoxybenzene 3,4-二甲氧基苄氯 4-碘藜芦醚 6-溴藜芦醛 3,4-二甲氧基苯乙胺 (Z)-1-[(3,4-Dimethoxyphenyl)methylene]-2-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (S)-(+)-1-(3',4'-dimethoxybenzyl)-6-benzyloxy-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline S-四氢罂粟碱 (+)-Vateamine 邻苯二甲醚 N-[((1R,2S,5R)-8-phenylmenthoxy)carbonyl]-1-(4,5-dimethoxybenzyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-1-carbonitrile N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2,2-trifluoroacetamide N-[((1R,2S,5R)-8-phenylmenthoxyl)carbonyl]-2-(3,4-dimethoxyphenyl)ethylamine 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-ol 3,4-二甲氧基苯乙烯 2-(3-(苄氧基)-4-甲氧基苯基)乙胺 (R)-ethyl 1-((S)-1,2-dihydroxyethyl)-6,7-dihydroxy-3,4-dihydroisoquinoline-2(1H)-carboxylate ((3,4-dimethoxyphenyl)ethynyl)trimethylsilane ethyl (R)-1-((S)-1,2-dihydroxyethyl)-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carboxylate (R)-1-((S)-1,2-Bis-ethoxycarbonyloxy-ethyl)-6,7-bis-ethoxycarbonyloxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid ethyl ester (+/-)-1,4-trans-4-acetoxy-1-(3,4-dimethoxybenzyl)-6-hydroxy-7-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline N-(2-((3,4-dimethoxyphenyl)ethynyl)-4,5-dimethoxyphenethyl)-2,2,2-trifluoroacetamide 2,2,2-trifluoro-N-[2-(2-iodo-4,5-dimethoxyphenyl)ethyl]acetamide 右旋奎宁酸 4-溴黎芦醚 (S)-valinol-tert-butyl ether formamidine of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 1-(3,4-dimethoxy)benzyl-1,2,3,4-tetrahydro-6-benzyloxy-7-methoxyisoquinoline (+)-Roemecarine 劳丹素 (S)-(+)-1-(3',4'-dimethoxybenzyl)-6-hydroxy-7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline 甲乙酐甲醛 (R)-2-ethoxycarbonyl-1-formyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 3,4-二氢罂粟碱 (+)-threo-N-(ethoxycarbonyl)hydroxynorlaudanosine 3,4-二甲氧基苄基溴 2-[(4S)-4,5-dihydro-4-(1-methylethyl)-2-oxazolyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (S)-valino tert-butyl ether formamidine of 3-benzyloxy-4-methoxy-1,2,3,4-tetrahydro-isoquinoline (S)-1-((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethane-1,2-diol

下游产品

3,4-二甲氧基苯甲醛 2,3,6,7-tetramethoxy-9,10-dihydro-anthracene