化合物简介
Flupentixol (INN), also known as flupenthixol (former BAN), marketed under brand names such as Depixol and Fluanxol is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1965 by Lundbeck. In addition to single drug preparations, it is also available as flupentixol/melitracen—a combination product containing both melitracen (a tricyclic antidepressant) and flupentixol. Flupentixol is not approved for use in the United States. It is, however, approved for use in the UK, Australia, Canada, Russian Federation, South Africa, New Zealand, Philippines and various other countries.
基本信息
中文名称
三氟噻吨
英文名称
flupenthixol
中文别名
4-(3-(2-(三氟甲基)-9H-噻吨-9-亚基)丙基)-1-哌嗪乙醇
英文别名
n7009、[3H]-(Z)-Flupentixol、siplaril、fluanxol、fluxanxol、Flupentiol、emergil、siplarol、lc44、flupentixol
CAS号
2709-56-0
分子式
C23H25F3N2OS
分子量
434.518
精确质量
434.164
PSA
52.01
LOGP
4.4775
编号系统
UNII
21HMQ851IS
物化性质
外观与性状
白色或灰白色固体
密度
1.306g/cm3
沸点
554.7ºC at 760mmHg
闪点
289.3ºC
折射率
1.607
安全信息
RTECS号
TL9900000
安全说明
36/37/39
WGK Germany
3
危险类别码
R20/21/22
危险品运输编码
UN 2811 6.1/PG 3
危险品标志
Xn
合成路线