化合物简介
Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria. Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole. Isoconazole nitrate may be used in combination with corticosteroid diflucortolone to increase its bioavailability.
基本信息
中文名称
异康唑
英文名称
1-[2-(2,4-dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole
中文别名
邻氯益康唑
英文别名
Isoconazolum、Travogen、Isoconazol、Isoconazole、Fazol
CAS号
27523-40-6
分子式
C18H14Cl4N2O
分子量
416.129
精确质量
413.986
PSA
27.05
LOGP
6.4548
编号系统
EINECS号
248-508-3
物化性质
密度
1.4g/cm3
沸点
555.1ºC at 760mmHg
闪点
289.5ºC
折射率
1.625
蒸汽压
8.55E-12mmHg at 25°C
