化合物简介
1,2-Piperidinedicarboxylic Acid 1-(Phenylmethyl) Ester is used to prepare disubstituted azetidinones as selective inhibitors of cysteine protease cathepsin K. It is also used to synthesize 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide (ABT-888) as the Poly(ADP-ribose) Polymerase (PARP) inhibitor for the treatment of cancer.
基本信息
中文名称
1-N-Cbz-2-哌啶甲酸
英文名称
1-CBZ-2-PIPERIDINECARBOXYLIC ACID
中文别名
1-CBZ-2-哌啶甲酸、1-苄氧羰基-2-哌啶甲酸、1-N-苄氧羰基-2-哌啶甲酸
英文别名
1-CBZ-PIPERIDINE-2-CARBOXYLIC ACID、N-CARBOBENZYLOXY-2-PIPERIDINECARBOXYLIC ACID、piperidine-1,2-dicarboxylic acid 1-benzyl ester、1-(CARBOBENZYLOXY)-2-PIPERIDINECARBOXYLIC ACID、N-benzyloxycarbonyl-D-pipecolinic acid、Cbz-DL-pipecolinic carboxylic acid、Z-PIPECOLIC ACID、1-((Benzyloxy)carbonyl)piperidine-2-carboxylic acid、N-Cbz-2-piperidinecarboxylic acid、1-(Carbobenzyloxy)-2-piperidinecarbozylicacid、N-Cbz-2-Piperidinecarboxylic acid、Z-PIP-OH、1-N-Cbz-piperidine-2-carboxylic acid、1-(benzyloxycarbonyl)-2-piperidinecarboxylic acid、Z-PIPECOLINIC ACID、N-CARBOBENZYLOXYPIPERIDINE-2-CARBOXYLIC ACID
CAS号
28697-07-6
分子式
C14H17NO4
分子量
263.289
精确质量
263.116
PSA
66.84
LOGP
2.2002
物化性质
密度
1.265 g/cm3
沸点
443.9ºC at 760 mmHg
安全信息
海关编码
2933399090
