化合物简介
Benzamil or benzyl amiloride is a potent blocker of the ENaC channel and also a sodium-calcium exchange blocker. It is a potent analog of amiloride, and is marketed as the hydrochloride salt (benzamil hydrochloride). As amiloride, benzamil has been studied as a possible treatment for cystic fibrosis, although with disappointing results.
基本信息
中文名称
苄基阿米洛利
英文名称
Benzamil
中文别名
苄基氨氯吡脒、苄基氨氯吡咪
英文别名
Benzyl amiloride、GNF-Pf-192、3,5-diamino-6-chloro-pyrazine-2-carboxylic acid benzylcarbamimidoyl-amide、3,5-diamino-N-(N\'-benzylcarbamimidoyl)-6-chloropyrazine-2-carboxamide
CAS号
2898-76-2
分子式
C13H14ClN7O
分子量
319.75
精确质量
319.095
PSA
142.8
LOGP
2.7927
编号系统
UNII
04659UUJ94
安全信息
安全说明
S26; S36
危险类别码
R36/37/38
危险品运输编码
UN 2811
海关编码
2934999090
合成路线
