百科

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

CAS号：294674-51-4

英文名：(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

分子式：C20H30O2

分子量：302.451

合成路线

(5R)-3-iodo-5-isopropyl-2-methylcyclohexa-1,3-diene

(5R)-3-iodo-5-isopropyl-2-methylcyclohexa-1,3-diene

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

(R)-4-((R)-3-Isopropyl-6-methyl-cyclohexa-1,5-dienyl)-2-((Z)-1-methyl-4-triisopropylsilanyloxy-but-1-enyl)-5-(3-trimethylsilanyl-prop-2-ynyl)-[1,3]dioxolane

(R)-4-((R)-3-Isopropyl-6-methyl-cyclohexa-1,5-dienyl)-2-((Z)-1-methyl-4-triisopropylsilanyloxy-but-1-enyl)-5-(3-trimethylsilanyl-prop-2-ynyl)-[1,3]dioxolane

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

(1R,3R,3aR,7R,7aR)-4-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,5,7a-hexahydroisobenzofuran-1-yl)-(Z)-pent-3-ene-1-ol

上游原料

(R)-4-((R)-3-Isopropyl-6-methyl-cyclohexa-1,5-dienyl)-2-((Z)-1-methyl-4-triisopropylsilanyloxy-but-1-enyl)-5-(3-trimethylsilanyl-prop-2-ynyl)-[1,3]dioxolane (5R)-3-iodo-5-isopropyl-2-methylcyclohexa-1,3-diene

下游产品

2,2-Dimethyl-propionic acid (R)-4-(tert-butyl-dimethyl-silanyloxy)-4-((1R,3R,3aR,7R,7aR)-7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydro-isobenzofuran-1-yl)-pentyl ester (3R,7R,8R,10S,11S,14R,15R,16R)-14-(tert-butyldimethylsiloxy)-3-isopropyl-6,10,14-trimethyl-15-oxatricyclo[6.6.1.00,0]pentadec-5-ene-10,11-diol (R)-4-((1R,3R,3aR,7R,7aR)-7-Isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydro-isobenzofuran-1-yl)-pentane-1,4-diol (1R,3R,3aR,7R,7aR)-2-[3-(7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl)-3(2R,3R)-methyloxiranyl]-ethanol (1'R,2R,4a'R,5'R,8'S,11'R,12'R,12a'R)-11'-((tert-butyldimethylsilyl)oxy)-1'-isopropyl-4',11'-dimethyl-2',4a',5',6',8',9',10',11',12',12a'-decahydro-1'H-spiro[oxirane-2,7'-[5,12]epoxybenzo[10]annulen]-8'-ol acetic acid (3R,7R,8R,11S,14R,15R,16R)-14-(tert-butyldimethylsilyloxy)-3-isopropyl-6,14-dimethyl-10-methylene-15-oxatricyclo[6.6.1.00,0]pentadec-5-en-11-yl ester