化合物简介
Apigenin 7-Glucuronide is a metabolite of Apigenin, which induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 uM) by inhibiting MAP kinase activity. Also inhibits the proliferation of malignant tumor cells by G2/M arrest and induces morphological differentiation. Apigenin has also been reported to enhance the gap juntion intracellular communication in liver cells.
基本信息
中文名称
芹菜素-7-葡萄糖醛酸
英文名称
Apigenin 7-glucuronide
中文别名
芹菜素-7-O-葡萄糖醛酸苷、灯盏花甲素
英文别名
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxane-2-carboxylic acid、Apigenin 7-O-glucuronide
CAS号
29741-09-1
分子式
C21H18O11
分子量
446.361
精确质量
446.085
PSA
187.12
LOGP
0.1422
编号系统
UNII
2CQ5KB3CH0
物化性质
密度
1.737g/cm3
沸点
841.8ºC at 760mmHg
闪点
299ºC
折射率
1.739
蒸汽压
4.28E-30mmHg at 25°C
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