合成路线
查看更多
首页
百科
齐多夫定
CAS号：30516-87-1
英文名：zidovudine
分子式：C10H13N5O4
分子量：267.241
上游原料
3'-azido-3'-deoxy-5'-O-thexyldimethylsilylthymidine
4,5-O-cyclohexylidene-2,3-dideoxy-aldehydo-D-glycero-trans-pent-2-enose
(2R,3R)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-5-methoxytetrahydrofuran-3-yl trifluoromethanesulfonate
4,5-O-cyclohexylidene-2,3-dideoxy-3-azido-aldehydo-D-glycero-pentanose
(2S,3S)-3-azido-5,5-bis(benzyloxy)pentane-1,2-diol
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxy-oxophosphanium
methyl 2-deoxy-3,5-O-isopropylidene-αβ-D-threo-pentafuranoside
ethyl (E)-5,5-bis(benzyloxy)pent-2-enoate
(S)-(-)-5-羟甲基-2(5H)-呋喃酮
5,5-Dibenzyloxy-2E-penten-1-ol
methyl 3,5-O-isopropylidene-2-O-<(methylthio)-thiocarbonyl>-α-D-xylofuranoside
5-苯甲酰基-3-乙烷磺酰基-2-溴胸苷
3'-叠氮基-3'-脱氧-5'-胸苷酸
2-(((2S,3S,5R)-3-azido-5-(phenylthio)tetrahydrofuran-2-yl)methoxy)-4-methoxy-5-methylpyrimidine
1-O-acetyl-3-azido-2,3-dideoxy-5-O-(tert-butyldimethylsilyl)-α,β-D-erythro-pentofuranose
2-Chloro-4-methoxy-5-methylpyrimidine
methyl 5-O-(tert-butyldiphenylsilyl)-2-deoxy-α,β-D-threo-pentofuranoside
O-benzyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate
AZT guanidine salt
P-(tert-butyl)-3'-azido-3'-deoxythymidine 5'-hydrogenphosphonate
司他夫定
O-isopropyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate
2,3’-脱水胸苷
1-(3-azido-2,3-dideoxy-β-D-erythro-pentofuranosyl)-4-methoxy-5-methyl-2(1H)-pyrimidinone
methyl 3,5-O-isopropylidene-αβ-D-xylofuranoside
((2R,3R)-3-(2,2-bis(benzyloxy)ethyl)oxiran-2-yl)methanol
3'-azido-3'-deoxy-5'-O-(4,4'-dimethoxytrityl)thymidine
5-甲基脲嘧啶
3'-Azido-5'-O-(4-methoxybenzoyl)-3'-deoxythymidine
4(R)-azido-5(S)-[[(tert-butyldimethylsilyl)oxy]methyl]-3,4-dihydro-5H-furan-2-one
(2S,3S)-3-azido-5,5-bis(benzyloxy)pentane-1,2-diyl dibenzoate
O-cyclohexyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate
methyl 2-deoxy-αβ-D-threo-pentafuranoside
(S)-(+)-3-(2,2-二甲基-1,3-二氧戊环-4-基)-顺式-2-丙烯酸乙酯
adamantan-1-yl (((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) phosphonate
adamantan-1-yl (((2S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,5-dihydrofuran-2-yl)methyl) phosphonate
((2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl neopentyl phosphonate
3'-叠氮基-3'-脱氧-5'-O-三苯甲基胸苷
((2R,3S,5R)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-(methylsulfonyloxy)-tetrahydrofuran-2-yl)methyl benzoate
5-O-苯甲酰基-2,3-脱水胸腺嘧啶脱氧核苷
Methyl 5-O-benzoyl-3-O-tosyl-2-deoxy-D-xylofuranoside
O-ethyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate
5-O-(tert-butyldimethylsilyl)-2,3-dideoxy-L-glyceropentonic acid γ-lactone
O,O′-二(三甲基甲硅烷基)胸苷
(+)-(2E,4S)-5-Acetoxy-4-(formyloxy)-2-pentenal
1-[5-O-Benzoyl-3-azido-2,3-dideoxy-α,β-D-erythro-pentofuranosyl]-thymine
methyl 3-azido-2,3-dideoxy-5-O-tert-butyldiphenylsilyl-α,β-D-erythro-pentofuranoside
胸苷
下游产品
3’-叠氮-2’,3’-双脱氧腺苷
1-[(2R,4S,5S)-5-(hydroxymethyl)-4-isothiocyanatooxolan-2-yl]-5-methylpyrimidine-2,4-dione
O-hexadecyl-O'-(3'-azido-3'-deoxythymidin-5'-yl) phosphonate
[(2S,3S,5S)-3-azido-5-(2,6-diaminopurin-9-yl)oxolan-2-yl]methanol
1-[(2R,4S,5S)-4-azido-5-(dichlorophosphoryloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoate
5-甲基脲嘧啶
1-[(2R,4S,5S)-5-(羟基甲基)-4-甲基氨基四氢呋喃-2-基]-5-甲基嘧啶-2,4-二酮
双十二烃基磷酸
3’-氨基-2’,3’-双脱氧胸苷
5'-(1,4-二氢-1-甲基-3-吡啶基羰基)-3'-叠氮基-3'-脱氧胸苷
3'-叠氮基-3'-脱氧-5'-胸苷酸
1-[(2R,4S,5S)-4-[4,5-bis(hydroxymethyl)triazol-1-yl]-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
dihexadecoxy(oxo)phosphanium
[(2S,3S,5R)-3-叠氮基-5-(5-甲基-2,4-二氧代嘧啶-1-基)四氢呋喃-2-基]甲基[(2R,3S,4S,5R,6S)-3,4,5,6-四羟基四氢吡喃-2-基]甲基磷酸氢酯
2-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidin-4-one
呋喃
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl 2-(4-phenylpiperazin-1-yl)acetate
甲醇
[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl 2-morpholin-4-ylacetate
3'-叠氮基-2,6-二氨基嘌呤-2',3'-二脱氧核糖甙
3'-氨基-2',3'-双脱氧鸟苷
二氧化碳
L-胱氨酸
(4S)-4-amino-5-[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy]-5-oxopentanoic acid
5-O-苯甲酰基-3-叠氮基-3-脱氧胸腺嘧啶脱氧核苷
