化合物简介
Remimazolam (CNS-7056) is a benzodiazepine derivative drug, developed by PAION, in collaboration with Japanese licensee Ono Pharmaceutical as an alternative to the short-acting imidazobenzodiazepine midazolam, for use in induction of anaesthesia and conscious sedation for minor invasive procedures. Remimazolam was found to be both faster acting and shorter lasting than midazolam, and human clinical trials showed a faster recovery time and predictable, consistent pharmacokinetics, suggesting some advantages over existing drugs for these applications.
基本信息
中文名称
瑞米唑仑
英文名称
Remimazolam
中文别名
瑞马唑仑
英文别名
methyl (S)-3-(8-bromo-1-methyl-6-(pyridin-2-yl)-4H-benzo[f]imidazo[1,2-a][1,4]diazepin-4-yl)propanoate、IMI030、methyl 3-[(4S)-8-bromo-1-methyl-6-pyridin-2-yl-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate、CNS 7056、CN-7056
CAS号
308242-62-8
分子式
C21H19BrN4O2
分子量
439.305
精确质量
438.069
PSA
69.37
LOGP
3.6191
编号系统
UNII
7V4A8U16MB
合成路线
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