化合物简介
Estradiol cypionate (INN, USAN) (brand names Depo-Estradiol, Depofemin, Estradep, and many others), or estradiol cipionate, also known as estradiol 3-cyclopentylpropionate, is a synthetic estrogen ester, specifically the 3-cyclopentylpropanoyl ester, of the natural estrogen estradiol. It was first introduced in 1952 by Upjohn in the United States, and has been in widespread use since. Estradiol cypionate behaves as a sustained-release prodrug to estradiol, and therefore is considered to be natural estrogen.
基本信息
中文名称
环戊丙酸雌二醇
英文名称
β-Estradiol 17-cypionate
中文别名
Β-雌二醇-17-脓蓝素、β-雌二醇-17-环戊丙酸酯
英文别名
Depofemin、β-Estradiol 17-Cyclopentylpropionate、Estradiol Cypionate
CAS号
313-06-4
分子式
C26H36O3
分子量
396.562
精确质量
396.266
PSA
46.53
LOGP
6.1305
编号系统
UNII
7E1DV054LO
物化性质
外观与性状
白色或灰白色结晶粉末
密度
1.15g/cm3
沸点
532.8ºC at 760mmHg
熔点
≥300°C(lit.)
闪点
207.7ºC
折射率
1.579
安全信息
RTECS号
KG4600000
安全说明
S53-S22-S36/37/39-S45-S26
危险类别码
R20/21/22; R36/37/38; R45; R46; R61
WGK Germany
3
危险品标志
T
生产方法及用途
用途
长效雌激素。