4-乙基-4-羟基-3,4,12,14-四氢-1H-吡喃并[3'4':6,7]吲哚嗪并[1,2-b]喹啉-3,14-二酮

CAS号：31456-25-4

英文名：4-ethyl-4-hydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione

分子式

C20H16N2O4

熔点

257ºC

密度

1.51g/cm3

分子量

348.352

沸点

757ºC at 760mmHg

溶解度

信号词

危险品标志

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基本信息

中文名称

4-乙基-4-羟基-3,4,12,14-四氢-1H-吡喃并[3'4':6,7]吲哚嗪并[1,2-b]喹啉-3,14-二酮

英文名称

4-ethyl-4-hydroxy-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione

中文别名

英文别名

dl-camptothecin、4-ethyl-4-hydroxy-1,12-dihydro-4H-pyrano[3\',4\':6,7]indolizino[1,2-b]quinoline-3,14-dione、Camptothecine,(+-)、camptothecin、4-ethyl-4-hydroxy-1h-pyrano[3\',4\':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione

CAS号

31456-25-4

分子式

C20H16N2O4

分子量

348.352

精确质量

348.111

PSA

81.42

LOGP

2.0796

物化性质

密度

1.51g/cm3

沸点

757ºC at 760mmHg

熔点

257ºC

闪点

411.6ºC

折射率

1.746

安全信息

安全说明

S45

危险类别码

R25

危险品标志

合成路线

34141-35-0

(+/-)-20-deoxycamptothecin

31456-25-4

4-乙基-4-羟基-3,4,12,14-四氢-1H-吡喃并[3'4':6,7]吲哚嗪并[1,2-b]喹啉-3,14-二酮

上游原料

共找到77个上游原料 >

58610-61-0

ethyl 5-cyano-4-methyl-6-oxo-1H-pyridine-2-carboxylate

145474-08-4

methyl 4-ethyl-3,10-dioxo-3,4,6,7,8,10-hexahydro-1H-pyrano[3,4-f]indolizine-5-carboxylate

58610-63-2

7-甲基-1,5-二氧代-1,2,3,5-四氢吲哚嗪-6-甲腈

120461-65-6

dimethyl 3-chloro-2-pentenedioate

145474-06-2

4-(carbomethoxymethyl)-5-carbomethoxy-1,6-cyclopentano-2-pyridone

55857-35-7

2-[(4-methylphenyl)iminomethyl]aniline

上游原料

ethyl 5-cyano-4-methyl-6-oxo-1H-pyridine-2-carboxylate methyl 4-ethyl-3,10-dioxo-3,4,6,7,8,10-hexahydro-1H-pyrano[3,4-f]indolizine-5-carboxylate 7-甲基-1,5-二氧代-1,2,3,5-四氢吲哚嗪-6-甲腈 dimethyl 3-chloro-2-pentenedioate 4-(carbomethoxymethyl)-5-carbomethoxy-1,6-cyclopentano-2-pyridone 2-[(4-methylphenyl)iminomethyl]aniline (2-Bromo-quinolin-3-yl)-methanol 4-ethyl-4-hydroxy-1,7-dihydro-4H-pyrano[3,4-c]pyridine-3,8-dione 4-乙基-7,8-二氢-4-羟基-1H-吡喃并[3,4-f]吲嗪-3,6,10(4H)-三酮 3-((benzyloxy)carbonyl)-6-oxohex-4-yn-3-yl benzoate ethyl N-(diphenylmethylene)-2-amino-4-pentenoate benzyl 2-ethyl-2-hydroxy-5-((tetrahydro-2H-pyran-2-yl)oxy)pent-3-ynoate 8-ethyl-1-hydroxy-8-methoxy-2,3,5,8-tetrahydro-1H-6-oxa-3a-aza-cyclopenta[b]naphthalene-4,7-dione ethyl bromo-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl] acetate ethyl 2-acetoxy-2-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]butanoate methyl 2-pyrrolidin-2-ylideneacetate (E)-6-benzylidene-4-ethyl-3,10-dioxo-3,4,6,7,8,10-hexahydro-1H-pyrano[3,4-f]indolizine-5-carboxylic acid (8-acetoxymethyl-9-oxo-9,11-dihydro-indolizino[1,2-b]quinolin-7-yl)-acetic acid ethyl ester 9,11-dihydro-α-ethyl-9-oxoindolizino[1,2-b]quinoline-7-acetic acid, methyl ester 2-methoxy-2-(5-oxo-6-trifluoromethanesulfonyloxy-1,2,3,5-tetrahydro-indolizin-7-yl)-butyric acid methyl ester ethyl 2-(6-((N-nitrosoacetamido)methyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate 6'-cyano-α-ethyl-2',3'-dihydro-5'-oxospiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, ethyl ester 4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl benzoate 2-(8-methylene-9-oxo-5b,6,7,8,9,11-hexahydro-indolizino[1,2-b]quinolin-7-yl)-butyric acid methyl ester ethyl (RS)-2-aminopent-4-enoate 7-(2-Bromo-quinolin-3-ylmethyl)-4-ethyl-4-hydroxy-1,7-dihydro-4H-pyrano[3,4-c]pyridine-3,8-dione 4-ethyl-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione 1,5-dioxo(5'-ethyl-2'H,5'H,6'H-6-oxopyrano)[3',4'-f]-Δ6(8)-tetrahydroindolizine 2',3'-二氢-7'-甲基-5'-氧代-螺[1,3-二氧戊环-2,1'(5'H)-吲嗪]-6'-甲腈 4-(1-carbomethoxypropyl)-5-carbomethoxy-1,6-cyclopentano-2-pyridone 1-(benzyloxy)-2-(5-ethoxy-4-formylfuran-3-yl)-1-oxobutan-2-yl benzoate 3-((benzyloxy)carbonyl)-6-hydroxyhex-4-yn-3-yl benzoate 4-ethyl-4,6,7,8-tetrahydro-1H-pyrano[3,4-f]indolizine-3,10-dione 4-ethyl-4-hydroxy-8-methoxy-1H-pyrano[3,4-c]pyridin-3(4H)-one 1,12-dihydro-4H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione O-methylcamptothecin 8-ethyl-8-methoxy-2,3,5,8-tetrahydro-1H-6-oxa-3a-aza-cyclopenta[b]naphthalene-1,4,7-trione 6-(acetamidomethyl)-1,1-(ethylenedioxy)-7-(1'-(ethoxycarbonyl)propyl)-5-oxo-Δ6(8)-tetrahydroindolizine 8-ethyl-8-methoxy-2,3,5,8-tetrahydro-1H-6-oxa-3a-aza-cyclopenta[b]naphthalene-4,7-dione ethyl acetoxy-[6-cyano-1,1-(ethylenedioxy)-5-oxo-1,2,3,5-tetrahydroindolizin-7-yl]acetate 4-ethyl-3,6,10-trioxo-3,4,6,7,8,10-hexahydro-1H-pyrano[3,4-f]indolizine-5-carboxylic acid (+/-)-20-deoxycamptothecin 2-溴喹啉 methyl 1-ethyl-3-hydroxy-4-methoxy-1,3-dihydrofuro[3,4-c]pyridine-1-carboxylate 6-cyano-1,1-(ethylenedioxy)-7-[(ethoxycarbonyl)methyl]-5-oxo-Δ6(8)-tetrahydroindolizine 2-(6-hydroxy-5-oxo-1,2,3,5-tetrahydro-indolizin-7-yl)-2-methoxybutyric acid methyl ester