化合物简介
Etomidate (USAN, INN, BAN) (marketed as Amidate) is a short-acting intravenous anaesthetic agent used for the induction of general anaesthesia and sedation for short procedures such as reduction of dislocated joints, tracheal intubation, and cardioversion. It was discovered at Janssen Pharmaceutica in 1964 and was introduced as an intravenous agent in 1972 in Europe and in 1983 in the United States.
基本信息
中文名称
依托咪酯
英文名称
etomidate
中文别名
R-(+)-1-(1-苯乙基)-1-氢-咪唑-5-甲酸乙酯、(R)-(+)-1-(1-苯乙基)-1-氢-咪唑-5-甲酸乙酯、(R)-1-(1-苯基乙基)-1H-咪唑-5-甲酸乙酯、乙苄咪唑
英文别名
(R)-Ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate、(R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylic Acid Ethyl Ester、PROPISCIN、R-1665、AMIDATE、RADENARCON、Etomidate、Amidate,R16659、D-ETOMIDATE、HYPNOMIDATE、Amidate R16659、Ethyl (R)-(+)-1-(1-Phenylethyl)-1H-imidazole-5-carboxylate
CAS号
33125-97-2
分子式
C14H16N2O2
分子量
244.289
精确质量
244.121
PSA
44.12
LOGP
2.6691
编号系统
MDL号
MFCD00869295
物化性质
外观与性状
白色粉末
密度
1.11g/cm3
沸点
391.5ºC at 760mmHg
熔点
72-74ºC
闪点
190.6ºC
折射率
1.561
稳定性
Stable at normal temperatures and pressures.
储存条件
2-8ºC
安全信息
安全说明
S36
危险类别码
R22
海关编码
2933990090
危险品标志
Xn
危险标志
GHS07, GHS09
危险性防范说明
P273
信号词
Warning
危险性描述
H302; H400
海关数据
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