化合物简介
Zomepirac is an orally effective non-steroidal anti-inflammatory drug (NSAID) that has antipyretic actions. It was developed by McNeil Pharmaceutical and approved by the FDA in 1980 and sold as the sodium salt, zomepirac sodium, under the brand name Zomax. Due to its clinical effectiveness, it was preferred by doctors in many situations and obtained a large share of the analgesics market; however, it was subsequently withdrawn in March 1983 due to its tendency to cause serious anaphylaxis in an unpredictable subset of the patient population.
基本信息
中文名称
佐美酸
英文名称
zomepirac
中文别名
英文别名
Zomax、5-(p-chlorobenzoyl)-1,4-dimethylpyrrole-2-acetic acid、Zomepirac [INN:BAN]、EINECS 251-474-2、ZOMEPIRAC SODIUM、5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrole-2-acetic acid、2-[5-(4-chlorobenzoyl)-1,4-dimethylpyrrol-2-yl]acetic acid、[3H]-Zomepirac、5-(4-chlorobenzoyl)-1,4-dimethylpyrrol-2-acetic acid、Zomepiracum [INN-Latin]、[5-(4-chlorobenzoyl)-1,4-dimethyl-1H-pyrrol-2-yl]acetic acid、Zomepiracum
CAS号
33369-31-2
分子式
C15H14ClNO3
分子量
291.73
精确质量
291.066
PSA
59.3
LOGP
2.845
编号系统
UNII
822G987U9J
物化性质
密度
1.28g/cm3
沸点
470.8ºC at 760mmHg
闪点
238.5ºC
折射率
1.595
安全信息
海关编码
2933990090