化合物简介
Nitromethaqualone is an analogue of methaqualone that has similar sedative and hypnotic properties. It is significantly more potent (10x) compared to the parent compound; the typical dose is approximately 25mg. However, the aromatic nitro group is metabolised to the corresponding aniline, which proved to be a mutagen. As a consequence, nitromethaqualone was not developed further due to toxicity concerns.
基本信息
中文名称
硝甲喹酮
英文名称
3-(2-methoxy-4-nitrophenyl)-2-methylquinazolin-4-one
中文别名
英文别名
nitromethaqualone、Nitrometaqualone、CHI 26、Parnox
CAS号
340-52-3
分子式
C16H13N3O4
分子量
311.292
精确质量
311.091
PSA
89.94
LOGP
3.1341
编号系统
UNII
7G855468ZM
物化性质
密度
1.36g/cm3
沸点
528ºC at 760 mmHg
闪点
273.1ºC
折射率
1.651
安全信息
海关编码
2933990090