百科

头孢西丁

头孢西丁

CAS号：35607-66-0

英文名：cefoxitin

分子式

C16H17N3O7S2

熔点

149 - 150ºC

密度

1.63 g/cm3

分子量

427.452

沸点

843.4ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

Cefoxitin is a semi-synthetic antibiotic derived from Cephamycin C, possessing high resistance to β-lactamase inactivation. An antibacterial.

基本信息

中文名称

头孢西丁

英文名称

cefoxitin

中文别名

3-氨基甲酰基氧甲基-7-甲氧基-7-(2-噻吩乙酰胺基)-8-氧代-5-硫-1-杂氮双环[4.2.0]辛-2-烯-2-甲酸、头孢西丁 USP

英文别名

Rephoxitin、Cefoxitin、cfx、CEFOXITIN ACID、Mefoxin、cephoxitin

CAS号

35607-66-0

分子式

C16H17N3O7S2

分子量

427.452

精确质量

427.051

PSA

201.8

LOGP

1.1277

编号系统

UNII

6OEV9DX57Y

物化性质

外观与性状

白色至灰白色结晶粉末

密度

1.63 g/cm3

沸点

843.4ºC at 760 mmHg

熔点

149 - 150ºC

折射率

1.692

储存条件

库房低温通风干燥

安全信息

危险品运输编码

UN 3077

海关编码

3003201300

包装等级

III

生产方法及用途

用途

原料药。

合成路线

(6R)-3-carbamoyloxymethyl-7c-methoxy-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

(6R)-3-carbamoyloxymethyl-7c-methoxy-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

头孢西丁

上游原料

共找到7个上游原料 >

diphenylmethyl (6R,7S)-7-carboxycarbonylamino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate

diphenylmethyl (6R,7S)-7-carboxycarbonylamino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate

diphenylmethyl (6R, 7S)-7-amino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate

diphenylmethyl (6R, 7S)-7-amino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate

(6R)-7t-[(R)-5-benzhydryloxycarbonyl-5-(2,2,2-trichloro-ethoxycarbonylamino)-pentanoylamino]-3-carbamoyloxymethyl-7c-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

(6R)-7t-[(R)-5-benzhydryloxycarbonyl-5-(2,2,2-trichloro-ethoxycarbonylamino)-pentanoylamino]-3-carbamoyloxymethyl-7c-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester

2-(((6R,7S)-2-((benzhydryloxy)carbonyl)-3-((((carboxycarbonyl)carbamoyl)oxy)methyl)-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoacetic acid

2-(((6R,7S)-2-((benzhydryloxy)carbonyl)-3-((((carboxycarbonyl)carbamoyl)oxy)methyl)-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoacetic acid

cephamycin C

2-噻吩乙酰氯

2-噻吩乙酰氯

上游原料

diphenylmethyl (6R,7S)-7-carboxycarbonylamino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate diphenylmethyl (6R, 7S)-7-amino-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylate (6R)-7t-[(R)-5-benzhydryloxycarbonyl-5-(2,2,2-trichloro-ethoxycarbonylamino)-pentanoylamino]-3-carbamoyloxymethyl-7c-methoxy-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester 2-(((6R,7S)-2-((benzhydryloxy)carbonyl)-3-((((carboxycarbonyl)carbamoyl)oxy)methyl)-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-7-yl)amino)-2-oxoacetic acid cephamycin C 2-噻吩乙酰氯 (6R)-3-carbamoyloxymethyl-7c-methoxy-8-oxo-7t-(2-thiophen-2-yl-acetylamino)-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester