百科

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

CAS号：368869-16-3

英文名：(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

分子式：C26H47IO3Si

分子量：562.64

合成路线

(E)-2-methyl-5-(triisopropylsilyloxy)pent-2-enal

(E)-2-methyl-5-(triisopropylsilyloxy)pent-2-enal

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

2,2-Dimethyl-propionic acid (R)-4-(tert-butyl-dimethyl-silanyloxy)-4-((1R,3R,3aR,7R,7aR)-7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydro-isobenzofuran-1-yl)-pentyl ester

2,2-Dimethyl-propionic acid (R)-4-(tert-butyl-dimethyl-silanyloxy)-4-((1R,3R,3aR,7R,7aR)-7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydro-isobenzofuran-1-yl)-pentyl ester

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

(1R,3R,3aR,7R,7aR)-4(R)-(tert-butyldimethylsilyloxy)-4-[3-(2-iodoallyl)-7-isopropyl-4-methyl-1,3,3a,6,7,7a-hexahydroisobenzofuran-1-yl]pentan-1-ol

上游原料

2,2-Dimethyl-propionic acid (R)-4-(tert-butyl-dimethyl-silanyloxy)-4-((1R,3R,3aR,7R,7aR)-7-isopropyl-4-methyl-3-prop-2-ynyl-1,3,3a,6,7,7a-hexahydro-isobenzofuran-1-yl)-pentyl ester (E)-2-methyl-5-(triisopropylsilyloxy)pent-2-enal

下游产品

(1'R,2R,4a'R,5'R,8'S,11'R,12'R,12a'R)-11'-((tert-butyldimethylsilyl)oxy)-1'-isopropyl-4',11'-dimethyl-2',4a',5',6',8',9',10',11',12',12a'-decahydro-1'H-spiro[oxirane-2,7'-[5,12]epoxybenzo[10]annulen]-8'-ol