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S-(4-硝基苄基)-6-硫肌苷

S-(4-硝基苄基)-6-硫肌苷

CAS号：38048-32-7

英文名：S-(4-Nitrobenzyl)-6-thioinosine

分子式

C17H17N5O6S

熔点

187-190°C(lit.)

密度

1.78g/cm3

分子量

419.412

沸点

770.2ºC at 760mmHg

溶解度

信号词

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化合物简介

It is a prototype inhibitor of the human equilibrative nucleoside transporter (hENT1), and is a high affinity ligand with a Kd of 0.1-1.0 nM. Nucleoside transporter inhibitors have potential therapeutic applications as anticancer, antiviral, cardioprotective, and neuroprotective agents.

基本信息

中文名称

S-(4-硝基苄基)-6-硫肌苷

英文名称

S-(4-Nitrobenzyl)-6-thioinosine

中文别名

英文别名

6-S-[(4-Nitrophenyl)methyl]-6-thioinosine

CAS号

38048-32-7

分子式

C17H17N5O6S

分子量

419.412

精确质量

419.09

PSA

184.64

LOGP

1.1615

编号系统

UNII

GV1L2DZM2Z

物化性质

密度

1.78g/cm3

沸点

770.2ºC at 760mmHg

熔点

187-190°C(lit.)

闪点

419.6ºC

折射率

1.807

储存条件

2-8ºC

安全信息

RTECS号

UO9025000

安全说明

S24/25

WGK Germany

3

合成路线

共找到3条合成路线 >

4-硝基-苯甲硫醇

4-硝基-苯甲硫醇

6-氯嘌呤核苷

6-氯嘌呤核苷

S-(4-硝基苄基)-6-硫肌苷

S-(4-硝基苄基)-6-硫肌苷

上游原料

共找到8个上游原料 >

[3,4-dibenzoyloxy-5-(6-chloropurin-9-yl)oxolan-2-yl]methyl benzoate

[3,4-dibenzoyloxy-5-(6-chloropurin-9-yl)oxolan-2-yl]methyl benzoate

(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(carbamimidoylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate hydrochloride

(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(carbamimidoylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate hydrochloride

1-乙酰基-三-苄氧基-罗伯糖

1-乙酰基-三-苄氧基-罗伯糖

2,3,5-三-O-乙酰基-6-氯嘌呤-9-β-D-呋喃核糖苷

2,3,5-三-O-乙酰基-6-氯嘌呤-9-β-D-呋喃核糖苷

6-氯嘌呤

6-氯嘌呤核苷

6-氯嘌呤核苷

下游产品

共找到8个下游商品 >

2-(hydroxymethyl)-5-(6-propylsulfanylpurin-9-yl)oxolane-3,4-diol

2-(hydroxymethyl)-5-(6-propylsulfanylpurin-9-yl)oxolane-3,4-diol

6-[[4-[N-(propylsulfonyl)amino]benzyl]thio]-9-(β-D-ribofuranosyl)purine

6-[[4-[N-(propylsulfonyl)amino]benzyl]thio]-9-(β-D-ribofuranosyl)purine

对硝基苯乙醇

对硝基苯乙醇

(2R,3R,4S,5R)-2-(6-((4-(hydroxyamino)benzyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

(2R,3R,4S,5R)-2-(6-((4-(hydroxyamino)benzyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

6-疏基嘌呤核苷

6-疏基嘌呤核苷

对硝基甲苯

对硝基甲苯

上游原料

[3,4-dibenzoyloxy-5-(6-chloropurin-9-yl)oxolan-2-yl]methyl benzoate (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(carbamimidoylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate hydrochloride 1-乙酰基-三-苄氧基-罗伯糖 2,3,5-三-O-乙酰基-6-氯嘌呤-9-β-D-呋喃核糖苷 6-氯嘌呤 6-氯嘌呤核苷 1-(氯甲基)-4-硝基苯 4-硝基-苯甲硫醇

下游产品

2-(hydroxymethyl)-5-(6-propylsulfanylpurin-9-yl)oxolane-3,4-diol 6-[[4-[N-(propylsulfonyl)amino]benzyl]thio]-9-(β-D-ribofuranosyl)purine 对硝基苯乙醇 (2R,3R,4S,5R)-2-(6-((4-(hydroxyamino)benzyl)thio)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 6-疏基嘌呤核苷对硝基甲苯 6-((propylthio)thio)-9-(β-D-ribofuranosyl)purine