4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

CAS号：380909-55-7

英文名：4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

分子式：C60H83NO9Si2

分子量：1018.47

合成路线

2-[(2R,3S,4S,5R,6R)-4-(3,4-Dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-ethanol

2-[(2R,3S,4S,5R,6R)-4-(3,4-Dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-ethanol

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

(2R,3S,5S,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-one

(2R,3S,5S,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-one

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxymethyl)-oxazole

4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxymethyl)-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

(2S,4R,6R)-2-{(2R,6R)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-6-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-tetrahydro-pyran-4-ol

(2S,4R,6R)-2-{(2R,6R)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-6-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-tetrahydro-pyran-4-ol

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

(2R,3R,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-ol

(2R,3R,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-ol

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

(2R,3S,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-(3,4-dimethoxy-benzyloxy)-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran

(2R,3S,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-(3,4-dimethoxy-benzyloxy)-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-chloromethyl-oxazole

4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-chloromethyl-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

4-(4-(tert-butyl-dimethyl-silanyloxy)-6-{6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazole

上游原料

4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-chloromethyl-oxazole (2R,3R,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-ol (2R,3S,4S,5R,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-(3,4-dimethoxy-benzyloxy)-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran (2R,3S,5S,6R)-2-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-3,5-dimethyl-6-[(triisopropylsilanyl)-ethynyl]-tetrahydro-pyran-4-one 2-[(2R,3S,4S,5R,6R)-4-(3,4-Dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-ethanol (2S,4R,6R)-2-{(2R,6R)-6-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-6-[2-(4-methoxy-benzyloxymethyl)-oxazol-4-yl]-tetrahydro-pyran-4-ol 4-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{(2R,6R)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methylene-tetrahydro-pyran-2-ylmethyl}-tetrahydro-pyran-2-yl)-2-(4-methoxy-benzyloxymethyl)-oxazole

下游产品

{6-[4-(tert-butyl-dimethyl-silanyloxy)-6-(2-{3-[4-(3,4-dimethoxy-benzyloxy)-6-ethynyl-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazol-4-yl)-tetrahydro-pyran-2-ylmethyl]-4-methylene-tetrahydro-pyran-2-yl}-acetaldehyde [(2R,6R)-6-((2R,4R,6R)-4-(tert-Butyl-dimethyl-silanyloxy)-6-{2-[(E)-3-((2R,3R,4S,5R,6R)-6-ethynyl-4-hydroxy-3,5-dimethyl-tetrahydro-pyran-2-yl)-propenyl]-oxazol-4-yl}-tetrahydro-pyran-2-ylmethyl)-4-methylene-tetrahydro-pyran-2-yl]-acetaldehyde