化合物简介
17-Hydroxypregnenolone (also 17-OH-pregnenolone and 17α-hydroxypregnenolone), is a C21 steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by the mitochondrial cytochrome P450 enzyme 17α-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline. High levels are also achieved during pregnancy.
基本信息
中文名称
17Alpha-羟基妊娠烯醇酮
英文名称
17α-hydroxypregnenolone
中文别名
17-羟基孕尿烯酮、3Β,17Α-二羟基-5-孕烯-20酮、17a-羟基孕烯醇酮
英文别名
17A-HYDROXY PREGNENOLONE、5-Pregnen-3.β.,17.α.-diol-20-one、17A-HYDROXYPREGENOLONE、17alpha-Hydroxy、17-Hydroxy Pregnenolone、17alpha-hydroxypregnenolone、17a-Hydroxypregnolone、HYDROXYPREGNENOLONE,17A、17ALPHA-HYDROXYPREGNENOLONE、17-OH PREG、Hydroxypregnenolone、17-OH-pregnenolone
CAS号
387-79-1
分子式
C21H32O3
分子量
332.477
精确质量
332.235
PSA
57.53
LOGP
3.6302
编号系统
EINECS号
206-862-6
物化性质
密度
1.15g/cm3
沸点
478.4ºC at 760 mmHg
闪点
257.2ºC
折射率
1.567
蒸汽压
3.69E-11mmHg at 25°C
上游原料
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