百科

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

CAS号：392322-47-3

英文名：(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

分子式：C35H62O2Si

分子量：542.951

合成路线

5,25R-胆甾烯-3beta,26-二醇

5,25R-胆甾烯-3beta,26-二醇

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

(8S,9S,10R,13R,14S,17R)-17-[(1R,5R)-6-(tert-Butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-4,4,10,13-tetramethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

(8S,9S,10R,13R,14S,17R)-17-[(1R,5R)-6-(tert-Butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-4,4,10,13-tetramethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

(2R,6R)-6-((3S,9S,10R,13R,14R,17R)-3-((tert-butyldimethylsilyl)oxy)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-1-ol

上游原料

5,25R-胆甾烯-3beta,26-二醇 (8S,9S,10R,13R,14S,17R)-17-[(1R,5R)-6-(tert-Butyl-dimethyl-silanyloxy)-1,5-dimethyl-hexyl]-4,4,10,13-tetramethyl-1,2,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

下游产品

tert-Butyl-[(3S,9S,10R,13R,14R,17R)-17-((R)-1,5-dimethyl-hex-5-enyl)-4,4,10,13-tetramethyl-2,3,4,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yloxy]-dimethyl-silane