丝裂霉素 A

丝裂霉素 A

CAS号：4055-39-4

英文名：mitomycin A

分子式

C16H19N3O6

熔点

159-161ºC (dec)

密度

1.5g/cm3

分子量

349.339

沸点

587.4ºC at 760 mmHg

溶解度

信号词

危险品标志

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化合物简介

The 6-methoxy analog of Mitomycin C. An antitumor antibiotic.

基本信息

中文名称

丝裂霉素 A

英文名称

mitomycin A

中文别名

英文别名

[(1aS,8S,8aR,8bS)-6,8a-Dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2,3,4]pyrrolo[1,2-a]indol-8-yl]methyl Carbamate、mitomycin-A、Mitomycin A、(1aS,8S,8aR,8bS)-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-6,8a-dimethoxy-5-methylazirino[2\',3\':3,4]pyrrolo[1,2-a]indole-4,7-dione

CAS号

4055-39-4

分子式

C16H19N3O6

分子量

349.339

精确质量

349.127

PSA

130.1

LOGP

0.0035

编号系统

UNII

87TMG6FJHV

物化性质

外观与性状

红色-紫罗兰色晶体

密度

1.5g/cm3

沸点

587.4ºC at 760 mmHg

熔点

159-161ºC (dec)

闪点

309.1ºC

折射率

1.638

储存条件

-20ºC Freezer

蒸汽压

8.83E-14mmHg at 25°C

合成路线

共找到28条合成路线 >

(8aS)-8a-bromoalbomitomycin A

(8aS)-8a-bromoalbomitomycin A

丝裂霉素 A

albomitomycin A

albomitomycin A

上游原料

共找到9个上游原料 >

丝裂霉素 C

重氮甲烷

甲醇钠

1a-acetyl-7-demethoxy-6,7-dihydro-7,7-(ethylenedioxy)-6-(phenylselenyl)mitomycin A

1a-acetyl-7-demethoxy-6,7-dihydro-7,7-(ethylenedioxy)-6-(phenylselenyl)mitomycin A

Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate

Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate

(8aS)-8a-bromoalbomitomycin A

(8aS)-8a-bromoalbomitomycin A

下游产品

共找到28个下游商品 >

NSC366469

(1S,2S,9S,9aR)-6-甲基-7-(4-甲基-2-噻唑基氨基)-9-(氨基甲酰氧基甲基)-9a-甲氧基-1,2-桥亚胺-2,3,9,9a-四氢-1H-吡咯并[1,2-a]吲哚-5,8-二酮

(1S,2S,9S,9aR)-6-甲基-7-(4-甲基-2-噻唑基氨基)-9-(氨基甲酰氧基甲基)-9a-甲氧基-1,2-桥亚胺-2,3,9,9a-四氢-1H-吡咯并[1,2-a]吲哚-5,8-二酮

泊非霉素

78142-77-5

6-(2-Phenoxyethoxy-6-deaminomitomycin C)

6-(2-Phenoxyethoxy-6-deaminomitomycin C)

NSC332374

上游原料

丝裂霉素 C 重氮甲烷甲醇钠 1a-acetyl-7-demethoxy-6,7-dihydro-7,7-(ethylenedioxy)-6-(phenylselenyl)mitomycin A Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate (8aS)-8a-bromoalbomitomycin A 7-O-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-9a-methoxymitosane 甲醇

下游产品

NSC366469 (1S,2S,9S,9aR)-6-甲基-7-(4-甲基-2-噻唑基氨基)-9-(氨基甲酰氧基甲基)-9a-甲氧基-1,2-桥亚胺-2,3,9,9a-四氢-1H-吡咯并[1,2-a]吲哚-5,8-二酮泊非霉素 78142-77-5 6-(2-Phenoxyethoxy-6-deaminomitomycin C) NSC332374 N-(4-(2,3,4,6-四-O-乙酰基-D-吡喃葡萄糖基)氧基)苯基丝裂霉素C NSC336239 NSC339668 NSC336240 BRN 4771482 Azirino[2',3'_3,4]pyrrolo[1,2-.α.]indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-hydroxy-8-(hydroxymethyl)-8a-methoxy-5-methyl-, 8-carbamate NSC345816 Azirino[2',4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-6-[(2,2-dimethoxyethyl)amino]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-, (1aR-(1a.α.,8.β.,8a.α.,8b.α.))- NSC339671 NSC357283 NSC364157 NSC347783 NSC345815 78327-30-7 6-Cyclopropylmethoxy-6-deaminomitomycin C AC1L3USN 7-Methoxy-1,2-(N-methylaziridino)mitosene NSC-328208 7-(2-羟基乙氧基)粘吐烷 NSC345817 7-N-Phenyl-mitomycin C NSC339670