化合物简介
Piperaquine is an antimalarial drug, a bisquinoline first synthesised in the 1960s, and used extensively in China and Indochina as prophylaxis and treatment during the next 20 years. Usage declined in the 1980s as piperaquine-resistant strains of P. falciparum arose and artemisinin-based antimalarials became available. However, Chinese scientists have been studying whether piperaquine can still be used therapeutically in combination with artemisinin.
基本信息
中文名称
磷酸哌喹
英文名称
Piperaquine phosphate
中文别名
1,3-双[4-(7-氯-喹啉-4-基)哌嗪-1-基]丙烷四磷酸盐四水合物
英文别名
Piperaquine tetraphosphate tetrahydrate、7-Chloro-4-[4-[3-[4-(7-chloroquinolin-4-yl)piperazin-1-yl]propyl]piperazin-1-yl]quinoline、piperaquinoline、PIRERAQUINE PHOSPHATE、Piperaquine
CAS号
4085-31-8
分子式
C29H32Cl2N6
分子量
535.511
精确质量
534.207
PSA
38.74
LOGP
5.4299
物化性质
密度
1.292g/cm3
沸点
721.1ºC at 760 mmHg
闪点
389.9ºC
折射率
1.664
安全信息
海关编码
2942000000
