化合物简介
Tolimidone (MLR-1023) is an allosteric Lyn kinase activator that has been shown to reduce blood glucose levels in mice. Studies show that Tolimidone is an effective insulin receptor-potentiating agent that is potentially capable of producing durable blood glucose-lowering activity in diabetics. Tolimidone is a candidate for the treatment of type 2 diabetes.
基本信息
中文名称
托利咪酮
英文名称
5-(3-methylphenoxy)-1H-pyrimidin-2-one
中文别名
5-(3-甲基苯酚基)-2-(1H)-嘧啶酮
英文别名
QCR-285、Tolimidone (USAN)、UNII-MU3JD8E9IS、5-(3-Methylphenoxy)- 2(1H)-pyrimidinone CP 26154、TOLIMIDONE、5-(m-Tolyloxy)-2-(1H)-pyrimidinon、Tolimidone [USAN:INN]、5-m-tolyloxy-1H-pyrimidin-2-one、5-(3-methylphenoxy)-2(1H)-pyrimidinone
CAS号
41964-07-2
分子式
C11H10N2O2
分子量
202.209
精确质量
202.074
PSA
54.98
LOGP
1.8706
编号系统
UNII
MU3JD8E9IS
物化性质
密度
1.22g/cm3
熔点
163-164ºC
折射率
1.598
安全信息
海关编码
2933599090
危险性描述
H319
信号词
Warning
危险标志
GHS07
危险性防范说明
P305 + P351 + P338
