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6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

CAS号：426219-18-3

英文名：6-(7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide

分子式：C18H17N3O2

分子量：307.346

合成路线

6-[1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide

6-[1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N,N-diisopropyl-2-naphthamide

6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N,N-diisopropyl-2-naphthamide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-溴-N-甲基-2-萘甲酰胺

6-溴-N-甲基-2-萘甲酰胺

5H-吡咯并[1,2-c]咪唑-7(6H)-酮

5H-吡咯并[1,2-c]咪唑-7(6H)-酮

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-溴-2-萘甲酸

6-溴-2-萘甲酸

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-bromo-N,N-diisopropyl-2-naphthamide

6-bromo-N,N-diisopropyl-2-naphthamide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

N,N-diisopropyl-6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)methyl]-2-naphthamide

N,N-diisopropyl-6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)methyl]-2-naphthamide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

N,N-diisopropyl-6-[(1-trityl-1H-imidazol-4-yl)carbonyl]-2-naphthamide

N,N-diisopropyl-6-[(1-trityl-1H-imidazol-4-yl)carbonyl]-2-naphthamide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

3-bromo-1-(1H-imidazol-4-yl)-1-propanone hydrobromide

3-bromo-1-(1H-imidazol-4-yl)-1-propanone hydrobromide

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

1-(1H-imidazol-4-yl)prop-2-en-1-one

1-(1H-imidazol-4-yl)prop-2-en-1-one

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-bromonaphthalene-2-carbonyl chloride

6-bromonaphthalene-2-carbonyl chloride

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

6-(6,7-二氢-7-羟基-5H-吡咯并[1,2-c]咪唑-7-基)-n-甲基-2-萘羧酰胺

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上游原料

正丁基锂 N,N-diisopropyl-6-[(1-trityl-1H-imidazol-4-yl)carbonyl]-2-naphthamide 6-bromo-N,N-diisopropyl-2-naphthamide 6-溴-N-甲基-2-萘甲酰胺 5H-吡咯并[1,2-c]咪唑-7(6H)-酮 6-溴-2-萘甲酸 N,N-diisopropyl-6-[1-hydroxy-1-(1-trityl-1H-imidazol-4-yl)methyl]-2-naphthamide 6-[1,3-dihydroxy-1-(1-trityl-1H-imidazol-4-yl)propyl]-N-methyl-2-naphthamide 6-(7-hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N,N-diisopropyl-2-naphthamide 3-bromo-1-(1H-imidazol-4-yl)-1-propanone hydrobromide 1-(1H-imidazol-4-yl)prop-2-en-1-one 6-bromonaphthalene-2-carbonyl chloride 甲胺

下游产品

6-[(7R)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide Orteronel; 6-[(7S)-7-羟基-6,7-二氢-5H-吡咯并[1,2-c]咪唑-7-基]-N-甲基-2-萘甲酰胺