百科

4-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-10,11-Dihydroxy-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynoic acid

CAS号：438222-59-4

英文名：4-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-10,11-Dihydroxy-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynoic acid

分子式：C32H46O8

分子量：558.703

合成路线

438222-39-0

tert-Butyl-((Z)-4-{(4S,5S)-2,2-dimethyl-5-[(E)-2-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-vinyl]-[1,3]dioxolan-4-yl}-but-3-enyloxy)-dimethyl-silane

438222-59-4

4-{(2R,6R)-6-[(7E,12E)-(2S,6S,10S,11S)-10,11-Dihydroxy-6-methoxymethoxy-2-methyl-13-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-4-methylene-trideca-7,12-dienyl]-5,6-dihydro-2H-pyran-2-yl}-but-2-ynoic acid

873195-70-1

(4R,5S)-2,2-Dimethyl-5-[(E)-2-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-vinyl]-[1,3]dioxolane-4-carbaldehyde

438222-59-4

438222-48-1

(R)-3-Methyl-4-((2R,6R)-6-vinyl-3,6-dihydro-2H-pyran-2-yl)-butyric acid methyl ester

438222-59-4

上游原料

(4R,5S)-2,2-Dimethyl-5-[(E)-2-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-vinyl]-[1,3]dioxolane-4-carbaldehyde tert-Butyl-((Z)-4-{(4S,5S)-2,2-dimethyl-5-[(E)-2-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-vinyl]-[1,3]dioxolan-4-yl}-but-3-enyloxy)-dimethyl-silane (R)-3-Methyl-4-((2R,6R)-6-vinyl-3,6-dihydro-2H-pyran-2-yl)-butyric acid methyl ester

下游产品

(3Z,9E)-(1R,7S,11S,15S,17R)-7-[(E)-(S)-1-Hydroxy-3-((S)-4-methyl-3,6-dihydro-2H-pyran-2-yl)-allyl]-11-methoxymethoxy-15-methyl-13-methylene-6,21-dioxa-bicyclo[15.3.1]henicosa-3,9,19-trien-5-one 16,17-deoxy-laulimalide