百科

环巴胺

环巴胺

CAS号：4449-51-8

英文名：Cyclopamine

分子式：C27H41NO2

分子量：411.62

合成路线

(2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-4'-(phenylsulfonyl)-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol

(2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-4'-(phenylsulfonyl)-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol

环巴胺

蒜黎芦碱

环巴胺

4-hydroxy-3-nitrobenzyl (3S,3'R,3a'S,6aS,6bS,6'S,7a'R,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3',3a',4,5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-4'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-carboxylate

4-hydroxy-3-nitrobenzyl (3S,3'R,3a'S,6aS,6bS,6'S,7a'R,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3',3a',4,5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-4'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-carboxylate

4-羟基-3-硝基苄醇

4-羟基-3-硝基苄醇

环巴胺

上游原料

蒜黎芦碱 (2'R,3S,3'R,3a'S,6aS,6bS,6'S,7a'R,11aS,11bR)-3',6',10,11b-tetramethyl-4'-(phenylsulfonyl)-1,2,3,3a',4,4',5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-3'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridin]-3-ol 4-hydroxy-3-nitrobenzyl (3S,3'R,3a'S,6aS,6bS,6'S,7a'R,9R,11aS,11bR)-3-hydroxy-3',6',10,11b-tetramethyl-1,2,3,3',3a',4,5',6,6a,6b,6',7,7',7a',8,11,11a,11b-octadecahydro-4'H-spiro[benzo[a]fluorene-9,2'-furo[3,2-b]pyridine]-4'-carboxylate

下游产品

(3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[1,2,5,6,6a,6b,7,8,11,11a-decahydrobenzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-one