百科

可待因酮

可待因酮

CAS号：467-13-0

英文名：codeinone

分子式

C18H19NO3

熔点

182-183ºC

密度

1.34 g/cm3

分子量

297.348

沸点

466.9ºC at 760 mmHg

溶解度

信号词

危险品标志

若想填写更详细的询价信息，请点击进入询价页面

点我

化合物简介

Codeinone is 1/3 as active as codeine as an analgesic but it is an important intermediate in the production of hydrocodone, a painkiller about 3/4 the potency of morphine; as well as of oxycodone, a painkiller roughly half again more or up to 1.7× the strength of morphine. The latter can also be synthesized from thebaine, however.

基本信息

中文名称

可待因酮

英文名称

codeinone

中文别名

英文别名

6-Oxocodeine、dihydrocodeine、hydrocodone、6-Codeinone、(4R,4aR,7aR,12bS)-9-methoxy-3-methyl-1,2,4,4a,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one、EINECS 207-386-1

CAS号

467-13-0

分子式

C18H19NO3

分子量

297.348

精确质量

297.136

PSA

38.77

LOGP

1.6472

编号系统

UNII

22B5AW0ANN

物化性质

密度

1.34 g/cm3

沸点

466.9ºC at 760 mmHg

熔点

182-183ºC

闪点

236.1ºC

折射率

1.656

储存条件

Controlled Substance, -20ºC Freezer

蒸汽压

6.84E-09mmHg at 25°C

安全信息

危险类别码

R22

合成路线

共找到5条合成路线 >

可待因

3-Methoxy-17-methyl-8,14-didehydro-4,5-epoxymorphinan-6-one

3-Methoxy-17-methyl-8,14-didehydro-4,5-epoxymorphinan-6-one

可待因酮

上游原料

共找到27个上游原料 >

碳酸钠

N-[2-[(3aR,9RS,9bS)-3a,8,9,9a-tetrahydro-9-(methanesulfonyloxy)-5-methoxy-3-oxo-9b-phenanthro[4,5-bcd]furanyl]ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide

N-[2-[(3aR,9RS,9bS)-3a,8,9,9a-tetrahydro-9-(methanesulfonyloxy)-5-methoxy-3-oxo-9b-phenanthro[4,5-bcd]furanyl]ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide

2-(2,2'-Bithiophen-5-yl)quinoline-4-carboxylic acid

2-(2,2'-Bithiophen-5-yl)quinoline-4-carboxylic acid

N-[2-((R)-5-(tert-butyldimethylsilyloxy)-6-oxocyclohex-1-enyl)ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide

N-[2-((R)-5-(tert-butyldimethylsilyloxy)-6-oxocyclohex-1-enyl)ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide

N-(2-((3aR,3a1S)-5-methoxy-3-oxo-3,8-dihydrophenanthro[4,5-bcd]furan-3a1(3aH)-yl)ethyl)-N-methyl-2,4-dinitrobenzenesulfonamide

N-(2-((3aR,3a1S)-5-methoxy-3-oxo-3,8-dihydrophenanthro[4,5-bcd]furan-3a1(3aH)-yl)ethyl)-N-methyl-2,4-dinitrobenzenesulfonamide

异丙醇铝

下游产品

共找到5个下游商品 >

7,8-二去氢-4,5alpha-环氧-3-甲氧基-17-甲基吗喃-6alpha-醇乙酸酯

7,8-二去氢-4,5alpha-环氧-3-甲氧基-17-甲基吗喃-6alpha-醇乙酸酯

acetic acid,6-methoxyphenanthrene-3,5-diol

acetic acid,6-methoxyphenanthrene-3,5-diol

7,8-环氧二氢可待因酮

7,8-环氧二氢可待因酮

14-Hydroxy Codeinone

14-Hydroxy Codeinone

N-甲基-2-羟基乙胺

N-甲基-2-羟基乙胺

上游原料

碳酸钠 N-[2-[(3aR,9RS,9bS)-3a,8,9,9a-tetrahydro-9-(methanesulfonyloxy)-5-methoxy-3-oxo-9b-phenanthro[4,5-bcd]furanyl]ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide 2-(2,2'-Bithiophen-5-yl)quinoline-4-carboxylic acid N-[2-((R)-5-(tert-butyldimethylsilyloxy)-6-oxocyclohex-1-enyl)ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide N-(2-((3aR,3a1S)-5-methoxy-3-oxo-3,8-dihydrophenanthro[4,5-bcd]furan-3a1(3aH)-yl)ethyl)-N-methyl-2,4-dinitrobenzenesulfonamide 异丙醇铝 N-[2-(5-acetoxy-6-oxocyclohex-1-enyl)ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide 4,5α-epoxy-3,6,8ξ-trimethoxy-17-methyl-morphin-6-ene N-methyl-N-[2-(6-oxocyclohex-1-enyl)ethyl]-2,4-dinitrobenzenesulfonamide N-(3-cyclopentenylpropyl)-N-methyl-2,4-dinitrobenzenesulfonamide 4,5α-epoxy-3,6,6-trimethoxy-17-methyl-morphinane 4,5α-epoxy-3,6,6-trimethoxy-17-methyl-morphin-7-ene N-[2-((5R,6R)-5-(tert-butyldimethylsilyloxy)-6-(3-(2,2-dimethoxyethyl)-2-iodo-6-methoxyphenoxy)cyclohex-1-enyl)]-N-methyl-2,4-dinitrobenzenesulfonamide 草酰氯 N-[2-((5R,6S)-5-(tert-butyldimethylsilyloxy)-6-hydroxycyclohex-1-enyl)ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide 可待因 N-(2-((3aR,3a1S,9aR)-9-hydroxy-5-methoxy-3-oxo-3,8,9,9a-tetrahydrophenanthro[4,5-bcd]furan-3a1(3aH)-yl)ethyl)-N-methyl-2,4-dinitrobenzenesulfonamide Phenol, 3-(2,2-dimethoxyethyl)-2-iodo-6-methoxy- N-[2-[(5aR,6R,9aS)-6,7-dihydro-6-hydroxy-1-(2,2-dimethoxyethyl)-4-methoxy-9a(5aH)-dibenzofuranyl]ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide N-(2-((5aR,6R,9aS)-6-((tert-butyldimethylsilyl)oxy)-1-(2,2-dimethoxyethyl)-4-methoxy-6,7-dihydrodibenzo[b,d]furan-9a(5aH)-yl)ethyl)-N-methyl-2,4-dinitrobenzenesulfonamide N-[2-[(5aR,9aS)-6,7-dihydro-1-(2,2-dimethoxyethyl)-4-methoxy-6-oxo-9a(5aH)-dibenzofuranyl]ethyl]-N-methyl-2,4-dinitrobenzenesulfonamide benzyl 2-((5R,6S)-5-(tert-butyldimethylsilyloxy)-6-hydroxycyclohex-1-enyl)ethylcarbamate 三乙胺可待因盐酸盐蒂巴因 benzyl N-[2-[(5aR,6R,9aS)-6-(tert-butyldimethylsilyloxy)-6,7-dihydro-1-(2,2-dimethoxyethyl)-4-methoxy-9a(5aH)-dibenzofuranyl]ethyl]carbamate benzyl 2-((5R,6R)-5-(tert-butyldimethylsilyloxy)-6-(3-(2,2-dimethoxyethyl)-2-iodo-6-methoxyphenoxy)cyclohex-1-enyl)ethylcarbamate

下游产品

7,8-二去氢-4,5alpha-环氧-3-甲氧基-17-甲基吗喃-6alpha-醇乙酸酯 acetic acid,6-methoxyphenanthrene-3,5-diol 7,8-环氧二氢可待因酮 14-Hydroxy Codeinone N-甲基-2-羟基乙胺