化合物简介
Rhein, also known as cassic acid, is a substance in the anthraquinone group obtained from rhubarb. Like all such substances, rhein is a cathartic. Rhein is commonly found as a glycoside such as rhein-8-glucoside or glucorhein. Rhein was first isolated in 1895. It is found in rhubarb species like Rheum undulatum and Rheum palmatum as well as in Cassia reticulata.
基本信息
中文名称
大黄酸
英文名称
Rhein
中文别名
1,8-二羟基-3-羧基蒽醌、9,10-二氢-4,5-二羟基-9,10-二氧代-2-蒽羧酸、4,5-二羟基蒽醌-2-羧酸、4,5-二羟蒽醌-2-羧酸
英文别名
1,8-dihydroxy-3-carboxy-9,10-anthraquinone、4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid、Cassic acid、2-Anthracenecarboxylic acid, 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-、Rheic acid、Rhubarb Yellow、1,8-dihydroxyanthraquinone-3-carboxylic acid、4,5-dihydroxyanthraquinone-2-carboxylic acid、1,8-dihydroxy-3-carboxyanthraquinone、9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid、Monorhein、4,5-Dihydroxyanthraquinone-2-carboxylic acid、9,10-dihydro-4,5-dihydroxy-9,10-dioxoanthracene-2-carboxylic acid、Rheic Acid、Chrysazin-3-carboxylic acid
CAS号
478-43-3
分子式
C15H8O6
分子量
284.22
精确质量
284.032
PSA
111.9
LOGP
1.5714
编号系统
MDL号
MFCD00009618
物化性质
外观与性状
为咖啡色针晶,升华后为黄色针晶。熔点 321-322℃,水溶性<0.1g/100mL
熔点
≥300°C(lit.)
储存条件
2-8°C
安全信息
RTECS号
CA9516000
安全说明
S26; S37/39
危险类别码
R36/37/38
WGK Germany
2
海关编码
2918990090
危险品标志
Xi
危险标志
GHS07
信号词
Warning
危险性描述
H315; H319; H335
危险性防范说明
P261; P305 + P351 + P338
生产方法及用途
用途
蛋白酶抑制剂。医药。
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