化合物简介
Oroxylin A is an O-methylated flavone, a chemical compound that can be found in the medicinal plant Scutellaria baicalensis and the Oroxylum indicum tree. It has demonstrated activity as a dopamine reuptake inhibitor, and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor. Oroxylin A has been found to improve memory consolidation in mice by elevating brain-derived neurotrophic factor (BDNF) levels in the hippocampus.
基本信息
中文名称
千层纸素A
英文名称
oroxylin A
中文别名
千层纸素、木蝴蝶素A
英文别名
5,7-dihydroxy-6-methoxyflavone、6-Methoxybaicalein、oroxyllin-A、5,7-dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one、Oroxylin、4H-1-Benzopyran-4-one, 5,7-dihydroxy-6-methoxy-2-phenyl-、6-methoxy-5,7-dihydroxyflavone、5,7-Dihydroxy-6-methoxy-2-phenyl-4H-1-benzopyran-4-one 5,7-Dihydroxy-6-methoxyflavone、5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one、baicalein 6-methyl ether、Oroxylin A、4H-1-Benzopyran-4-one,5,7-dihydroxy-6-methoxy-2-phenyl
CAS号
480-11-5
分子式
C16H12O5
分子量
284.263
精确质量
284.068
PSA
79.9
LOGP
2.8798
物化性质
密度
1.42g/cm3
沸点
540.9ºC at 760mmHg
熔点
195-197ºC
闪点
207.4ºC
折射率
1.668
蒸汽压
2.6E-12mmHg at 25°C
上游原料
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