化合物简介
Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular (tension) headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is advised, for example when driving motor vehicles. Additional uses of dichloralphenazone include sedation for the treatment of short-term insomnia, although there are probably better drug choices for the treatment of insomnia.
基本信息
中文名称
1,5-dimethyl-2-phenylpyrazol-3-one;2,2,2-trichloroethane-1,1-diol (1:2)
英文名称
1,5-dimethyl-2-phenylpyrazol-3-one,2,2,2-trichloroethane-1,1-diol
中文别名
英文别名
Kloralfenazon、Sominat、Dichloralantipyrin、Sedor、Dormuphar、dichloralphenazone、Welldorm、Dichloralantipyrine、Ibiodorm
CAS号
480-30-8
分子式
C15H18Cl6N2O5
分子量
519.032
精确质量
515.935
PSA
107.85
LOGP
2.819
编号系统
UNII
YYX637R279
物化性质
沸点
319ºC at 760 mmHg
蒸汽压
0.000348mmHg at 25°C
合成路线