化合物简介
A novel dual receptor tyrosine kinase inhibitor of the EGF and the VEGF receptor, for treatment of human HCC cell lines and in a s.c. xenograft model.
基本信息
中文名称
6-[4-[(4-乙基-1-哌嗪)甲基]苯基]-N-[(1R)-1-苯基乙基]-7H-吡咯并[2,3-d]嘧啶-4-胺
英文名称
6-(4-((4-ethyl-1-piperazinyl)methyl)phenyl)-N-((1R)-1-phenylethyl)-1H-Pyrrolo(2,3-D)pyrimidin-4-amine
中文别名
英文别名
Nifurpirinol [USAN:INN]、Furanace、Nifurpirinolum [INN-Latin]、Furpirinol、[6-[4-(4-ethyl-piperazine-1-ylmethyl)-phenyl]-7H-pyrrolo[2,3-d]pyrinidinpyrimidin-4-yl]-((R)-1-phenyl-ethyl)-amine、AEE788 (NVP-AEE788)、[6-[4-[(4-ethylpiperazine-1-yl)methyl]phenyl]-7H-pyrrolo[2,3-d]pyrimidine-4-yl]-((R)-1-phenylethyl)amine、Furpyrinol、Nifurpirinol、{6-[2-(5-nitro-furan-2-yl)-vinyl]-pyridin-2-yl}-methanol、{6-[4-(4-ethyl-piperazin-1-ylmethyl)-phenyl]-7H-pyrrolo[2.3-d]-pyrimidin-4-yl}-((R)-1-phenyl-ethyl)-amine、(R)-6-(4-((4-Ethylpiperazin-1-yl)methyl)phenyl)-N-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine、Furanace-10
CAS号
497839-62-0
分子式
C27H32N6
分子量
440.583
精确质量
440.269
PSA
63.31
LOGP
4.2332
编号系统
UNII
F9JLR95I3I
